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Spironolactone Side Effects List

Common Spironolactone Side Effects


The following Spironolactone Side Effects were reported by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers) and manufacturers.

It is important to know potential risks posed by drugs and health products. Staying informed can help you make right decisions and stay healthy.

You can read detailed reports by clicking on a side effect.




Abasia 5 reports0.14%
Abdominal Discomfort 8 reports0.23%
Abdominal Distension 10 reports0.28%
Abdominal Pain 14 reports0.40%
Abdominal Pain Lower 4 reports0.11%
Abdominal Pain Upper 14 reports0.40%
Abdominal Rebound Tenderness 2 reports0.06%
Acne 3 reports0.09%
Acne Cystic 2 reports0.06%
Activated Partial Thromboplastin Time Prolonged 2 reports0.06%
Acute Myocardial Infarction 2 reports0.06%
Acute Prerenal Failure 8 reports0.23%
Acute Right Ventricular Failure 2 reports0.06%
Adrenal Adenoma 3 reports0.09%
Adverse Reaction 2 reports0.06%
Agitation 4 reports0.11%
Agranulocytosis 3 reports0.09%
Alanine Aminotransferase Increased 5 reports0.14%
Alopecia 10 reports0.28%
Altered State Of Consciousness 7 reports0.20%
Amnesia 3 reports0.09%
Anaemia 24 reports0.68%
Anal Haemorrhage 3 reports0.09%
Anaphylactic Reaction 2 reports0.06%
Angina Pectoris 7 reports0.20%
Angioedema 3 reports0.09%
Angiopathy 3 reports0.09%
Anhedonia 6 reports0.17%
Anorexia 6 reports0.17%
Anosmia 3 reports0.09%
Anuria 3 reports0.09%
Anxiety 20 reports0.57%
Aphagia 2 reports0.06%
Arrhythmia 9 reports0.26%
Arthralgia 12 reports0.34%
Arthropathy 2 reports0.06%
Ascites 12 reports0.34%
Aspartate Aminotransferase Increased 6 reports0.17%
Asthenia 56 reports1.59%
Asthma 3 reports0.09%
Atrial Fibrillation 28 reports0.80%
Atrioventricular Block 6 reports0.17%
Atrioventricular Block Complete 11 reports0.31%
Atrioventricular Block First Degree 2 reports0.06%
Azotaemia 2 reports0.06%
Back Pain 22 reports0.63%
Balance Disorder 8 reports0.23%
Benign Prostatic Hyperplasia 2 reports0.06%
Bicytopenia 2 reports0.06%
Bile Duct Cancer 3 reports0.09%
Blood Albumin Decreased 3 reports0.09%
Blood Alkaline Phosphatase Increased 4 reports0.11%
Blood Amylase Increased 2 reports0.06%
Blood Bicarbonate Decreased 2 reports0.06%
Blood Bilirubin Increased 6 reports0.17%
Blood Cholesterol Increased 3 reports0.09%
Blood Creatine Increased 5 reports0.14%
Blood Creatinine Increased 48 reports1.37%
Blood Glucose Decreased 3 reports0.09%
Blood Glucose Increased 14 reports0.40%
Blood Ph Decreased 3 reports0.09%
Blood Potassium Decreased 14 reports0.40%
Blood Potassium Increased 50 reports1.42%
Blood Pressure Decreased 20 reports0.57%
Blood Pressure Diastolic Decreased 5 reports0.14%
Blood Pressure Fluctuation 2 reports0.06%
Blood Pressure Immeasurable 3 reports0.09%
Blood Pressure Inadequately Controlled 3 reports0.09%
Blood Pressure Increased 18 reports0.51%
Blood Pressure Systolic Decreased 3 reports0.09%
Blood Pressure Systolic Increased 3 reports0.09%
Blood Sodium Decreased 8 reports0.23%
Blood Urea Abnormal 2 reports0.06%
Blood Urea Increased 20 reports0.57%
Blood Urine Present 2 reports0.06%
Body Temperature Decreased 4 reports0.11%
Body Temperature Increased 3 reports0.09%
Bone Marrow Failure 3 reports0.09%
Bone Pain 6 reports0.17%
Bradycardia 36 reports1.03%
Brain Natriuretic Peptide Increased 4 reports0.11%
Breast Cancer 5 reports0.14%
Breast Enlargement 6 reports0.17%
Breast Mass 6 reports0.17%
Breast Pain 18 reports0.51%
Breast Swelling 4 reports0.11%
Breast Tenderness 7 reports0.20%
Bronchitis 5 reports0.14%
Bronchopneumonia 3 reports0.09%
Bruxism 2 reports0.06%
Budd-chiari Syndrome 3 reports0.09%
Bundle Branch Block Left 2 reports0.06%
Burning Sensation 5 reports0.14%
C-reactive Protein Increased 5 reports0.14%
Caesarean Section 2 reports0.06%
Carbon Dioxide Increased 2 reports0.06%
Cardiac Arrest 12 reports0.34%
Cardiac Disorder 10 reports0.28%
Cardiac Failure 25 reports0.71%
Cardiac Failure Congestive 20 reports0.57%
Cardiac Murmur 4 reports0.11%
Cardio-respiratory Arrest 4 reports0.11%
Cardiogenic Shock 11 reports0.31%
Cardiomegaly 4 reports0.11%
Cardiovascular Disorder 2 reports0.06%
Cellulitis 3 reports0.09%
Cerebral Haemorrhage 2 reports0.06%
Cerebral Infarction 2 reports0.06%
Cerebrovascular Accident 7 reports0.20%
Chest Discomfort 7 reports0.20%
Chest Pain 25 reports0.71%
Chills 4 reports0.11%
Cholecystectomy 2 reports0.06%
Cholecystitis Acute 4 reports0.11%
Cholecystitis Chronic 6 reports0.17%
Cholelithiasis 8 reports0.23%
Cholestasis 4 reports0.11%
Chromaturia 2 reports0.06%
Chronic Obstructive Pulmonary Disease 5 reports0.14%
Circulatory Collapse 4 reports0.11%
Coagulation Factor Xiii Level Decreased 2 reports0.06%
Coeliac Disease 3 reports0.09%
Cognitive Disorder 3 reports0.09%
Colitis Ischaemic 3 reports0.09%
Colitis Ulcerative 3 reports0.09%
Completed Suicide 3 reports0.09%
Condition Aggravated 27 reports0.77%
Confusional State 17 reports0.48%
Congestive Cardiomyopathy 2 reports0.06%
Constipation 14 reports0.40%
Contraindication To Medical Treatment 2 reports0.06%
Contusion 6 reports0.17%
Convulsion 8 reports0.23%
Coronary Artery Disease 4 reports0.11%
Coronary Artery Stenosis 3 reports0.09%
Cough 25 reports0.71%
Creatinine Renal Clearance Decreased 2 reports0.06%
Crepitations 2 reports0.06%
Crohn's Disease 3 reports0.09%
Crying 4 reports0.11%
Cutaneous Lupus Erythematosus 4 reports0.11%
Cyanosis 5 reports0.14%
Cyst 2 reports0.06%
Cytolytic Hepatitis 2 reports0.06%
Deafness 2 reports0.06%
Death 21 reports0.60%
Decreased Activity 2 reports0.06%
Decreased Appetite 9 reports0.26%
Deep Vein Thrombosis 8 reports0.23%
Dehydration 59 reports1.68%
Delirium 5 reports0.14%
Depressed Mood 3 reports0.09%
Depression 15 reports0.43%
Dermatitis 2 reports0.06%
Dermatitis Allergic 2 reports0.06%
Dermatitis Bullous 3 reports0.09%
Dermatitis Exfoliative 2 reports0.06%
Device Malfunction 3 reports0.09%
Device Related Infection 4 reports0.11%
Diabetes Mellitus 8 reports0.23%
Diabetes Mellitus Inadequate Control 2 reports0.06%
Diabetic Vascular Disorder 2 reports0.06%
Dialysis 4 reports0.11%
Diarrhoea 52 reports1.48%
Difficulty In Walking 2 reports0.06%
Dilatation Ventricular 3 reports0.09%
Discomfort 2 reports0.06%
Disease Progression 10 reports0.28%
Disorientation 5 reports0.14%
Disturbance In Attention 2 reports0.06%
Dizziness 40 reports1.14%
Dizziness Exertional 2 reports0.06%
Dizziness Postural 2 reports0.06%
Dry Eye 3 reports0.09%
Dry Mouth 2 reports0.06%
Dry Skin 7 reports0.20%
Duodenal Ulcer 2 reports0.06%
Dysarthria 2 reports0.06%
Dysgeusia 3 reports0.09%
Dyskinesia 3 reports0.09%
Dyspepsia 13 reports0.37%
Dysphagia 3 reports0.09%
Dyspnoea 81 reports2.31%
Dyspnoea Exertional 7 reports0.20%
Dysstasia 3 reports0.09%
Eczema 3 reports0.09%
Ejection Fraction Decreased 2 reports0.06%
Electrocardiogram Change 4 reports0.11%
Electrocardiogram Qrs Complex Prolonged 5 reports0.14%
Electrocardiogram Qt Prolonged 4 reports0.11%
Electrocardiogram T Wave Peaked 5 reports0.14%
Electrolyte Imbalance 6 reports0.17%
Embolic Stroke 2 reports0.06%
Emotional Distress 7 reports0.20%
Encephalopathy 3 reports0.09%
Epistaxis 9 reports0.26%
Erythema 6 reports0.17%
Faeces Discoloured 6 reports0.17%
Fall 25 reports0.71%
Fatigue 46 reports1.31%
Fear 6 reports0.17%
Fear Of Eating 9 reports0.26%
Feeling Abnormal 3 reports0.09%
Feeling Cold 4 reports0.11%
Feeling Hot 3 reports0.09%
Flatulence 10 reports0.28%
Fluid Overload 4 reports0.11%
Fluid Retention 8 reports0.23%
Flushing 6 reports0.17%
Furuncle 3 reports0.09%
Gait Disturbance 7 reports0.20%
Gallbladder Disorder 6 reports0.17%
Gamma-glutamyltransferase Increased 3 reports0.09%
Gastrointestinal Disorder 4 reports0.11%
Gastrointestinal Haemorrhage 6 reports0.17%
Gastrooesophageal Reflux Disease 12 reports0.34%
Gingival Bleeding 3 reports0.09%
Glomerular Filtration Rate Decreased 4 reports0.11%
Gout 3 reports0.09%
Gynaecomastia 55 reports1.57%
Haematemesis 5 reports0.14%
Haematocrit Decreased 5 reports0.14%
Haematoma 4 reports0.11%
Haemodialysis 11 reports0.31%
Haemoglobin Decreased 13 reports0.37%
Haemoptysis 8 reports0.23%
Haemorrhage 5 reports0.14%
Haemorrhoids 5 reports0.14%
Hair Texture Abnormal 3 reports0.09%
Hallucination 6 reports0.17%
Headache 20 reports0.57%
Heart Rate Decreased 9 reports0.26%
Heart Rate Increased 7 reports0.20%
Heart Rate Irregular 4 reports0.11%
Hepatic Cirrhosis 8 reports0.23%
Hepatic Encephalopathy 4 reports0.11%
Hepatic Failure 7 reports0.20%
Hepatic Fibrosis 3 reports0.09%
Hepatic Lesion 4 reports0.11%
Hepatic Necrosis 4 reports0.11%
Hepatic Neoplasm Malignant 6 reports0.17%
Hydrocele 3 reports0.09%
Hyperglycaemia 9 reports0.26%
Hyperhidrosis 5 reports0.14%
Hyperkalaemia 208 reports5.92%
Hypersensitivity 13 reports0.37%
Hypertension 21 reports0.60%
Hypoacusis 4 reports0.11%
Hypoaesthesia 10 reports0.28%
Hypocalcaemia 5 reports0.14%
Hypoglycaemia 7 reports0.20%
Hypokalaemia 17 reports0.48%
Hyponatraemia 33 reports0.94%
Hypophagia 5 reports0.14%
Hypotension 43 reports1.22%
Hypovolaemia 6 reports0.17%
Ill-defined Disorder 5 reports0.14%
Impaired Driving Ability 3 reports0.09%
Inappropriate Antidiuretic Hormone Secretion 4 reports0.11%
Incorrect Dose Administered 4 reports0.11%
Infection 6 reports0.17%
Inflammation 3 reports0.09%
Inflammatory Bowel Disease 3 reports0.09%
Injection Site Haematoma 4 reports0.11%
Injection Site Pain 3 reports0.09%
Injury 14 reports0.40%
Insomnia 13 reports0.37%
International Normalised Ratio Increased 8 reports0.23%
Jaundice 4 reports0.11%
Joint Swelling 3 reports0.09%
Lactic Acidosis 6 reports0.17%
Lethargy 3 reports0.09%
Leukocytosis 4 reports0.11%
Limb Discomfort 4 reports0.11%
Liver Disorder 4 reports0.11%
Liver Function Test Abnormal 3 reports0.09%
Local Swelling 4 reports0.11%
Loss Of Consciousness 13 reports0.37%
Lower Respiratory Tract Infection 5 reports0.14%
Malaise 26 reports0.74%
Melaena 3 reports0.09%
Menstruation Irregular 6 reports0.17%
Mental Disorder 4 reports0.11%
Mental Status Changes 5 reports0.14%
Metabolic Acidosis 6 reports0.17%
Metabolic Alkalosis 3 reports0.09%
Mobility Decreased 4 reports0.11%
Multi-organ Failure 9 reports0.26%
Muscle Spasms 12 reports0.34%
Muscle Twitching 4 reports0.11%
Muscular Weakness 12 reports0.34%
Musculoskeletal Pain 4 reports0.11%
Musculoskeletal Stiffness 3 reports0.09%
Myalgia 7 reports0.20%
Myocardial Infarction 16 reports0.46%
Nasopharyngitis 4 reports0.11%
Nausea 50 reports1.42%
Neoplasm Malignant 3 reports0.09%
Nervousness 9 reports0.26%
Neutropenia 6 reports0.17%
Nipple Disorder 3 reports0.09%
Nipple Pain 13 reports0.37%
No Adverse Event 3 reports0.09%
Nodal Rhythm 6 reports0.17%
Oedema 15 reports0.43%
Oedema Peripheral 31 reports0.88%
Oestrogen Receptor Assay Positive 3 reports0.09%
Off Label Use 12 reports0.34%
Oligodipsia 3 reports0.09%
Oral Intake Reduced 3 reports0.09%
Oropharyngeal Pain 3 reports0.09%
Orthostatic Hypotension 6 reports0.17%
Osteoarthritis 3 reports0.09%
Osteoporosis 3 reports0.09%
Overdose 5 reports0.14%
Pain 37 reports1.05%
Pain In Extremity 11 reports0.31%
Palpitations 8 reports0.23%
Pancreatitis 3 reports0.09%
Papule 4 reports0.11%
Paraesthesia 6 reports0.17%
Parkinson's Disease 3 reports0.09%
Photosensitivity Reaction 3 reports0.09%
Platelet Count Decreased 7 reports0.20%
Pleural Effusion 7 reports0.20%
Pneumonia 16 reports0.46%
Polyuria 4 reports0.11%
Product Quality Issue 4 reports0.11%
Product Substitution Issue 8 reports0.23%
Productive Cough 4 reports0.11%
Prostate Cancer 3 reports0.09%
Prostatic Specific Antigen Increased 3 reports0.09%
Pruritus 23 reports0.65%
Psoriasis 3 reports0.09%
Psychiatric Symptom 3 reports0.09%
Pulmonary Embolism 18 reports0.51%
Pulmonary Hypertension 6 reports0.17%
Pulmonary Oedema 8 reports0.23%
Pyrexia 23 reports0.65%
Rash 22 reports0.63%
Rash Erythematous 5 reports0.14%
Rash Macular 5 reports0.14%
Rash Maculo-papular 3 reports0.09%
Rash Pruritic 4 reports0.11%
Rectal Haemorrhage 5 reports0.14%
Renal Disorder 6 reports0.17%
Renal Failure 41 reports1.17%
Renal Failure Acute 103 reports2.93%
Renal Failure Chronic 6 reports0.17%
Renal Impairment 28 reports0.80%
Renal Injury 5 reports0.14%
Respiratory Distress 4 reports0.11%
Respiratory Failure 4 reports0.11%
Respiratory Tract Infection 3 reports0.09%
Retching 3 reports0.09%
Rhabdomyolysis 5 reports0.14%
Rhinorrhoea 5 reports0.14%
Right Ventricular Failure 3 reports0.09%
Scar 5 reports0.14%
Sepsis 6 reports0.17%
Somnolence 12 reports0.34%
Stevens-johnson Syndrome 7 reports0.20%
Stomatitis 4 reports0.11%
Stress 6 reports0.17%
Sudden Death 6 reports0.17%
Suicidal Ideation 4 reports0.11%
Swelling 6 reports0.17%
Swelling Face 5 reports0.14%
Syncope 16 reports0.46%
Systemic Lupus Erythematosus 5 reports0.14%
Tachycardia 7 reports0.20%
Therapeutic Agent Toxicity 3 reports0.09%
Thirst 4 reports0.11%
Thrombocytopenia 9 reports0.26%
Thrombosis 3 reports0.09%
Toxic Epidermal Necrolysis 8 reports0.23%
Toxic Skin Eruption 4 reports0.11%
Toxicity To Various Agents 6 reports0.17%
Transient Ischaemic Attack 4 reports0.11%
Treatment Noncompliance 5 reports0.14%
Tremor 8 reports0.23%
Type 2 Diabetes Mellitus 3 reports0.09%
Ulcer Haemorrhage 3 reports0.09%
Unevaluable Event 8 reports0.23%
Unresponsive To Stimuli 3 reports0.09%
Upper Gastrointestinal Haemorrhage 4 reports0.11%
Urinary Incontinence 5 reports0.14%
Urinary Tract Infection 8 reports0.23%
Urticaria 7 reports0.20%
Uterine Cancer 4 reports0.11%
Ventricular Hypokinesia 3 reports0.09%
Ventricular Tachycardia 7 reports0.20%
Vertigo 3 reports0.09%
Vision Blurred 9 reports0.26%
Visual Impairment 7 reports0.20%
Vomiting 33 reports0.94%
Weight Decreased 17 reports0.48%
Weight Increased 19 reports0.54%
White Blood Cell Count Decreased 3 reports0.09%
White Blood Cell Count Increased 6 reports0.17%

Displaying 400 Spironolactone side effects


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