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Spironolactone Oedema Side Effects

Spironolactone Oedema Side Effect Reports


The following Spironolactone Oedema side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Oedema, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Paraesthesia, Oedema

This Oedema side effect was reported by a consumer or non-health professional from US. A 65-year-old female patient (weight:NA) experienced the following symptoms/conditions: hormone level abnormal. The patient was prescribed Spironolactone Tablets 100mg (dosage: NA), which was started on Jun 04, 2013. Concurrently used drugs: NA. When starting to take Spironolactone Tablets 100mg the consumer reported the following symptoms:
  • Paraesthesia
  • Oedema
These side effects may potentially be related to Spironolactone Tablets 100mg.
Cardiac Failure, Pneumonitis, Asthenia, Productive Cough, Pyrexia, Oedema, Anaemia, Dyspnoea Exertional

This Oedema Spironolactone side effect was reported by a physician from ES on Jun 10, 2013. A male , 59 years of age, weighting 174.2 lb, was treated with Spironolactone. The patient presented the following health conditions:
  • Cardiac Failure
  • Pneumonitis
  • Asthenia
  • Productive Cough
  • Pyrexia
  • Oedema
  • Anaemia
  • Dyspnoea Exertional
. Spironolactone dosage: Daily Dose 25 Mg. Additional drugs used at the same time: NA. The patient was hospitalized.
Blood Pressure Fluctuation, Oedema

This is a Spironolactone side effect report of a 59-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: hypertension, who was treated with Spironolactone (dosage:NA, start time: 2000), combined with:
  • Hctz
  • Allegra D
  • Vitamins (And Various Supplements)
, and developed a serious reaction and a Oedema side effect. The patient presented with:
  • Blood Pressure Fluctuation
  • Oedema
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from hypertension, resulting in Oedema.

Arrhythmia, Oedema, Dyspnoea, Renal Failure Chronic, Mitral Valve Incompetence, Cardiac Failure, Blood Pressure Decreased

A female patient (weight: NA) from GERMANY with the following symptoms: oedema,hypertension started Spironolactone treatment (dosage: 50 Mg, Per Day) on Sep 10, 2010. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Arrhythmia
  • Oedema
  • Dyspnoea
  • Renal Failure Chronic
  • Mitral Valve Incompetence
  • Cardiac Failure
  • Blood Pressure Decreased
. Concurrently used drugs:
  • Lisinopril (10 Mg, Per Day)
  • Bisoprolol (10 Mg, Per Day)
  • Torsemide (10 Mg, Qd)
  • Beta Blocking Agents
  • Anticoagulants
  • Calcium Channel Blockers
  • Amiodarone Hcl (200 Mg, Per Day)
  • Rasilez (300 Mg, Per Day)
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Oedema.
Oedema, Respiratory Distress, Dyspnoea, Nodal Rhythm, Hyperkalaemia, Body Temperature Decreased, Atrioventricular Block, Heart Rate Decreased, Blood Creatinine Increased

A patient from UNITED STATES was prescribed and started Spironolactone on Nov 21, 2011. Patient felt the following Spironolactone side effects: oedema, respiratory distress, dyspnoea, nodal rhythm, hyperkalaemia, body temperature decreased, atrioventricular block, heart rate decreased, blood creatinine increased Additional patient health information: male , 70 years of age, The consumer reported the following symptoms: . Spironolactone dosage: NA. Concurrently used drugs:
  • Valsartan
  • Insulin
  • Carvedilol
The patient was hospitalized.
Oedema, Weight Increased, Pyrexia, Right Ventricular Failure

This report suggests a potential Spironolactone Oedema side effect(s) that can have serious consequences. A 32-year-old female patient from GERMANY (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: NA) starting Feb 03, 2011. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Oedema
  • Weight Increased
  • Pyrexia
  • Right Ventricular Failure
Drugs used concurrently:
  • Tracleer
  • Euthyrox
  • Kalinor-retard P
  • Torem
  • Revatio
  • Sti571/cgp57148b (Unk)
  • Marcumar
The patient was hospitalized. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Oedema, may still occur.
Decreased Activity, Discomfort, Oedema

An adverse event was reported by a pharmacist on Sep 10, 2010 by a Female taking Spironolactone (dosage: Unk) was diagnosed with and. Location: UNITED STATES , 89 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: decreased activity, discomfort, oedema. Additional medications/treatments:
Associated medications used:
  • Furosemide (Unk)
Atrial Fibrillation, Back Pain, Dehydration, Dyspepsia, Fear Of Eating, Gastrooesophageal Reflux Disease, Hypertension, Nausea, Oedema

This Oedema problem was reported by a health professional from UNITED KINGDOM. A 43-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jun 29, 2007 a consumer started treatment with Spironolactone (dosage: 50 Mg, Unk). The following drugs/medications were being taken at the same time:
  • Lisinopril
  • Irbesartan
  • Acomplia
  • Aspirin (5 Mg, Unk)
  • Atenolol (50 Mg, 1x/day)
  • Atorvastatin (80 Mg, 1x/day)
  • Codeine (120 Mg, Unk)
  • Furosemide (40 Mg, 1x/day)
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Atrial Fibrillation
  • Back Pain
  • Dehydration
  • Dyspepsia
  • Fear Of Eating
  • Gastrooesophageal Reflux Disease
  • Hypertension
  • Nausea
  • Oedema
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Oedema, may become evident only after a product is in use by the general population.
Atrial Fibrillation, Back Pain, Dehydration, Dyspepsia, Fear Of Eating, Gastrooesophageal Reflux Disease, Hypertension, Nausea, Oedema

This is a Spironolactone side effect report of a 43-year-old female patient (weight: NA) from UNITED KINGDOM. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: 50 Mg, Unk) starting Jun 29, 2007. Concurrently used drugs:
  • Lisinopril
  • Irbesartan
  • Acomplia
  • Aspirin (5 Mg, Unk)
  • Atenolol (50 Mg, 1x/day)
  • Atorvastatin (80 Mg, 1x/day)
  • Codeine (120 Mg, Unk)
  • Furosemide (40 Mg, 1x/day)
Soon after that, the consumer experienced the following of symptoms:
  • Atrial Fibrillation
  • Back Pain
  • Dehydration
  • Dyspepsia
  • Fear Of Eating
  • Gastrooesophageal Reflux Disease
  • Hypertension
  • Nausea
  • Oedema
The patient was hospitalized. This opens a possibility that Spironolactone could cause Oedema and that some female patients may be more susceptible.
Atrial Fibrillation, Back Pain, Dehydration, Dyspepsia, Fear Of Eating, Gastrooesophageal Reflux Disease, Hypertension, Nausea, Oedema

This Oedema side effect was reported by a health professional from UNITED KINGDOM on Oct 21, 2009. A patient from UNITED KINGDOM , 43 years of age, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: atrial fibrillation, back pain, dehydration, dyspepsia, fear of eating, gastrooesophageal reflux disease, hypertension, nausea, oedema. Spironolactone dosage: NA.
Associated medications used:
  • Lisinopril
  • Irbesartan
  • Acomplia
  • Aspirin (5 Mg, Unk)
  • Atenolol (50 Mg, Monthly)
  • Atorvastatin (80 Mg, 1x/day)
  • Codeine (120 Mg, Unk)
  • Furosemide (40 Mg, Monthly)
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Bereavement Reaction, Blood Oestrogen Increased, Depression, Erectile Dysfunction, Gender Identity Disorder, Gynaecomastia, Oedema, Suicidal Ideation

This Oedema side effect was reported by a physician from TURKEY. A 59-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Spironolactone (dosage: Unk), which was started on NS. Concurrently used drugs:
  • Digoxin (Unk)
When starting to take Spironolactone the consumer reported the following symptoms:
  • Bereavement Reaction
  • Blood Oestrogen Increased
  • Depression
  • Erectile Dysfunction
  • Gender Identity Disorder
  • Gynaecomastia
  • Oedema
  • Suicidal Ideation
These side effects may potentially be related to Spironolactone.
Anal Haemorrhage, Atrial Fibrillation, Back Pain, Constipation, Dehydration, Fear Of Eating, Hypertension, Nausea, Oedema

This Oedema Spironolactone side effect was reported by a health professional from UNITED KINGDOM on Jun 25, 2009. A Patient , 43 years of age, was treated with Spironolactone. The patient presented the following health conditions:
  • Anal Haemorrhage
  • Atrial Fibrillation
  • Back Pain
  • Constipation
  • Dehydration
  • Fear Of Eating
  • Hypertension
  • Nausea
  • Oedema
. Spironolactone dosage: 50 Mg, Unk. Additional drugs used at the same time:
  • Acomplia (20 Mg, Unk)
  • Irbesartan (150 Mg, 1x/day)
  • Lisinopril (20 Mg, 1x/day)
  • Aspirin (75 Mg, 1x/day)
  • Atenolol (50 Mg, 1x/day)
  • Atorvastatin (80 Mg, 1x/day)
  • Bisoprolol
  • Codeine (30 Mg, 1x/day)
The patient was hospitalized.
Atrial Fibrillation, Back Pain, Decreased Activity, Dehydration, Dyspepsia, Fear Of Eating, Gastrooesophageal Reflux Disease, Hypertension, Oedema

This is a Spironolactone side effect report of a 43-year-old female patient (weight:NA) from UNITED KINGDOM, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:50 Mg, Po, start time: NS), combined with:
  • Lisinopril
  • Rimonabant
  • Irbesartan
  • Acetylsalicylic Acid
  • Omeprazole
  • Furosemide
  • Isosorbide Mononitrate
  • Ispaghula Husk
, and developed a serious reaction and a Oedema side effect. The patient presented with:
  • Atrial Fibrillation
  • Back Pain
  • Decreased Activity
  • Dehydration
  • Dyspepsia
  • Fear Of Eating
  • Gastrooesophageal Reflux Disease
  • Hypertension
  • Oedema
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from NA, resulting in Oedema.
Blood Potassium Increased, Dyspnoea, Oedema

A 72-year-old patient (weight: NA) from UNITED STATES with the following symptoms: cardiac failure congestive,hypertension started Spironolactone treatment (dosage: 200mg Daily Po) on Jan 01, 2006. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Blood Potassium Increased
  • Dyspnoea
  • Oedema
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Oedema.
Alopecia, Lupus Nephritis, Oedema, Systemic Lupus Erythematosus Rash

A female patient from was prescribed and started Spironolactone on Feb 02, 2005. After Spironolactone was administered, patient encountered several Spironolactone side effects: alopecia, lupus nephritis, oedema, systemic lupus erythematosus rash Additional patient health information: Female , 59 years of age, weighting 137.0 lb, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: 25 Mg (25 Mg, Daily), Oral. Concurrently used drugs:
  • Fosinopril Sodium
  • Ascorbic Acid
  • Magnesium Oxide (magnesium Oxide)
  • Tocopherol (tocopherol)
  • Calcium (calcium)
  • Lecithin (lecithin)

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Oedema Causes and Reviews


Edema means swelling caused by fluid in your body's tissues. It usually occurs in the feet, ankles and legs, but it can involve your entire body.

Causes of edema include

  • Eating too much salt
  • Sunburn
  • Heart failure
  • Kidney disease
  • Liver problems from cirrhosis
  • Pregnancy
  • Problems with lymph nodes, especially after mastectomy
  • Some medicines
  • Standing or walking a lot when the weather is warm

To keep swelling down, your health care provider may recommend keeping your legs raised when sitting, wearing support stockings, limiting how much salt you eat, or taking a medicine called a diuretic - also called a water pill.


Spironolactone Oedema Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
Blood Creatinine Increased (48)
Fatigue (46)
Hypotension (43)
Renal Failure (41)
Dizziness (40)
Pain (37)
Bradycardia (36)
Vomiting (33)
Hyponatraemia (33)
Oedema Peripheral (31)
Atrial Fibrillation (28)
Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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