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Gastric Low-grade MALT Lymphoma With Helicobacter Pylori Positive | Prognostic Study of Gastric MALT Lymphoma After Eradication of Helicobacter Pylori

Gastric Low-grade MALT Lymphoma With Helicobacter Pylori Positive research study

What is the primary objective of this study?

To survey the grade of gastric MALT lymphoma after eradication of Helicobacter pylori

Who is eligible to participate?

Inclusion criteria: - gastric low-grade mucosa-associated lymphoid tissue (MALT) lymphoma with Helicobacter pylori positive - The stages of MALT lymphoma are Lugano International Conference classification Stage I or II 1 and Wotherspoon grade 4 or 5 Exclusion criteria: - With diffuse large B-cell lymphoma - Have been treated to gastric mucosa-associated lymphoid tissue (MALT) lymphoma - Corresponding to contraindication of each drug

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Gastric Low-grade MALT Lymphoma With Helicobacter Pylori Positive

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:Rabeprazole SodiumThe following 3 drugs are taken orally at the same time twice daily for 7 days: rabeprazole sodium 10 mg, amoxicillin hydrate 750 mg, and clarithromycin 200 mg. The dose of clarithromycin may be properly increased as needed, although the upper limit is 400 mg twice daily. If Helicobacter pylori eradication with proton pump inhibitor, amoxicillin, and clarithromycin fails, the following 3 drugs will be taken at the same time twice daily for 7 days as an alternative treatment for adults: rabeprazole sodium 10 mg, amoxicillin hydrate 750 mg, and metronidazole 250 mg.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Treatment Arm 1 Rabeprazole Sodium

Study Status

Completed

Start Date: January 13, 2011

Completed Date: November 17, 2016

Phase:

Type: Observational

Design:

Primary Outcome: Response rate of gastric low-grade MALT lymphoma by eradication of Helicobacter pylori

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Katsuya Sugizaki

Lead Sponsor: Eisai Co., Ltd.

Collaborator:

More information:https://clinicaltrials.gov/show/NCT01264822

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