Acne | the Comparison Efficacy of Azithromycin With Doxycycline in the Treatment of Acne Vulgaris

Acne research study

What is the primary objective of this study?

a comparison of efficacy and adverse side effects occurrence of Doxycycline and Azithromycin in the management of moderate acne vulgaris

Who is eligible to participate?

Inclusion Criteria: - Between 18 to 30 year old - Moderate facial Acne(At least 10 inflammatory lesions with maximum 3 nodules and pseudocysts Exclusion Criteria: - Pregnancy - Breast Feeding - Acne Fulminant - Acne conglobate - Isotretinoin therapy within past 6 months - topical treatment in last 2 weeks - use of systemic antibiotic in the last month - Hyperandrogenism symptoms - Menstrual irregularity

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:DoxycyclineCap 100mg- 100mg/daily

Drug:AzithromycinAzithromycin: Cap 250 mg- 500 mg single dose/daily - 3 times per week

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.



Study Status

Unknown status

Start Date: August 2006

Completed Date: February 2008

Phase: Phase 2

Type: Interventional


Primary Outcome: change in acne lesions

Secondary Outcome: global response rates, patient's own assessment, side effects and compliance

Study sponsors, principal investigator, and references

Principal Investigator: Parviz Toossi, M.D.

Lead Sponsor: Shahid Beheshti University of Medical Sciences


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