Acne Scars | The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars

Acne Scars research study

What is the primary objective of this study?

Our study involves the evaluation of a high potency chemical peel in its efficacy and safety profile for the treatment of acne scars. This chemical peel regime is a high potency peel of 70% glycolic acid combined with vitamin C that is purported to provide a good balance between yielding results and patient safety. We aim to evaluate its efficacy and safety profile of a single application. The study design is based on a single group that compares pre- vs post-intervention. 10 patients with atrophic acne scars of skin type I-IV will be recruited. Potential benefits include improvement of post acne scars with a short downtime and risks include post peel hyper pigmentation and scarring. We believe that this treatment will be highly beneficial to patients with post acne scarring. This chemical peel regime has good efficacy and safety profile for the treatment of acne scars.

Who is eligible to participate?

Inclusion Criteria: 1. Atrophic scars 2. Skin type I to IV Exclusion Criteria: 1. Pregnancy, breastfeeding 2. Active dermatitis (on the face), rosacea, allergic rhinitis, active herpes simplex 3. Known hypersensitivity 4. Previous keloids 5. Laser ablative procedures within the last month 6. Chemical peels within the last 6 months 7. Used oral retinoids in the past 6 months 8. Used topical retinoids in the past one week 9. Used scrub, AHA, skin irritant for the past 24h 10. Presence of facial warts or fungal infections 11. Photoallergies 12. Prior poor reaction to a chemical peel 13. Radiotherapy 14. Skin type V and VI 15. Patients with predominantly ice pick and boxcar scars

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Acne Scars

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:70% glycolic acid

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Single ArmSingle arm study - pre and post peel assessment

Study Status

Unknown status

Start Date: May 2014

Completed Date: November 2014

Phase: Phase 2

Type: Interventional


Primary Outcome: Efficacy Assessment

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: National University Hospital, Singapore


More information:

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