Pain, Postoperative | Naproxen for Acute Pain After Surgery: A Randomized, Placebo-Controlled Trial
Pain, Postoperative research study
What is the primary objective of this study?
The purpose of this study is to determine whether using an additional 48 hours of oral
naproxen, after other post-operative pain medications have been stopped, will be effective in
reducing opiate pain medication requirements and contribute to improved pain management.
Who is eligible to participate?
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:naproxenopaque pale orange suspension: 20mL q12h x 4 doses mixed in juice.
Drug:placeboopaque pale orange suspension: 20mL q12h x 4 doses mixed in juice
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Start Date: March 2008
Completed Date: June 2008
Phase: Phase 4
Primary Outcome: cumulative opiate dose administered, as recorded on the computerized medication administration record (CMAR)
Secondary Outcome: patient reported pain scores
Study sponsors, principal investigator, and references
Principal Investigator: Tuan Dinh, RPh
Lead Sponsor: Hamilton Health Sciences Corporation
Starck PL, Sherwood GD, Adams-McNeill J, Thomas EJ. Identifying and addressing medical errors in pain mismanagement. Jt Comm J Qual Improv. 2001 Apr;27(4):191-9. Review.