Treatment Resistant Anxiety Disorders | Anxiety Treatment Inspired by Dialectical Behavior Therapy (DBT)

Treatment Resistant Anxiety Disorders research study

What is the primary objective of this study?

The main interest in this study is to investigate if it is possible to use strategies from Dialectical Behavior Therapy (DBT) to increase effectiveness of ordinary Cognitive Behavioral Therapy (CBT) for patients with anxiety disorders. For the patients included in this study, previous exposure-based treatment should have been unsuccessful (drop-out, relapse or lack of positive results after treatment).

Who is eligible to participate?

Inclusion Criteria: - Currently diagnosed with an anxiety disorder. To be included, the level of anxiety in a critical situation should be high and of a more acute type, unlike the lower more generalized anxiety in for example generalized anxiety disorder. - Previous exposure-based treatment should have been unsuccessful (drop-out, relapse or lack of positive results after treatment). Exclusion Criteria: - Severe depression. - Psychotic disorder. - A documented neuropsychiatric diagnosis.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Treatment Resistant Anxiety Disorders

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Behavioral:DBT-inspired anxiety treatmentIn short, the treatment is 24 sessions consisting of skills-training strategies and exposure strategies. The idea is that the patient during the treatment will learn and practice the skills needed to handle exposures.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

DBT-inspired exposure treatmentDBT-inspired exposure treatment.

Study Status


Start Date: March 2012

Completed Date: October 2014

Phase: N/A

Type: Interventional


Primary Outcome: Change in anxiety (Clark, D. M., Ehlers, A., McManus, F., Hackmann, A., Fennell, M., Campbell, H., Flower, T., Davenport, C., Louis, B., 2003).

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: Örebro County Council


More information:

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