Anxiety Disorders | Delivery of Anxiety Disorder Treatment in Addictions Centers
Anxiety Disorders research study
What is the primary objective of this study?
Anxiety disorders are highly prevalent among those with substance use disorders, but the majority of addictions treatment centers provide little to no evidence-based treatment for anxiety disorders. Furthermore, tension reduction models suggest that treating anxiety should also improve substance use outcomes. This study is aimed at improving symptoms for people who have substance use and anxiety problems. The study is comparing regular Intensive Outpatient treatment for addiction to Intensive Outpatient treatment for addiction plus treatment for anxiety disorders. Clinicians at a community addictions clinic will participate by receiving training in delivering cognitive behavioral therapy for anxiety disorders and will deliver the treatment to the patient participants. They will also complete some questionnaires. Patient participants will be asked to complete a baseline assessment. Those who are eligible will be randomly assigned to one of the two treatment groups. Those who are assigned to addiction treatment as usual will continue their regular care at the Matrix Institute. Participants who are assigned to also receive the anxiety treatment will be asked to participate in 6, 90-min treatment sessions and an orientation session. All participants will be asked to complete post-treatment and follow-up assessments. The assessments should take approximately 1 hour, and the follow-up assessment will be completed 6 months after treatment is over. It is hypothesized that those who get the additional anxiety disorder treatment will show greater improvement in anxiety and substance use outcomes than those who get Intensive Outpatient Program without the anxiety disorder treatment.
Who is eligible to participate?
Inclusion Criteria: - 18-60 years old - speak English - meet diagnostic criteria for at least one anxiety disorder - score at least an 8 on the OASIS (see Assessments), indicating at least moderate but clinically significant anxiety symptoms - be enrolled in the Intensive Outpatient Program (IOP) at the Matrix Institute (community partner) - meet diagnostic criteria for substance abuse or dependence Exclusion Criteria: - have unstable medical conditions - marked cognitive impairment - active suicidal intent or plan - active psychosis - unstable Bipolar I disorder.
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Substance Use Disorders
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Behavioral:CALM-SUD6-session group for anxiety disorders. Cognitive behavioral therapy including self-monitoring, relaxation, cognitive restructuring, exposure therapy, and relapse prevention. In addition, participants in this arm are also enrolled in an Intensive Outpatient Program for their substance use disorder. The program is run by an outpatient addictions facility and includes up to 16 weeks of groups that meet 3 to 4 times per week in addition to up to 10 individual sessions of therapy. The group model includes motivational interviewing, cognitive behavioral therapy, contingency management, and relapse prevention skills.
Behavioral:Treatment as usualThe program is run by an outpatient addictions facility and includes up to 16 weeks of groups that meet 3 to 4 times per week in addition to up to 10 individual sessions of therapy. The group model includes motivational interviewing, cognitive behavioral therapy, contingency management, and relapse prevention skills.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
CALM-SUDParticipants receive the adaptation of the Coordinated Anxiety Learning and Management (CALM) protocol that demonstrated effectiveness in a large primary care sample. CALM will be adapted for those with anxiety and substance use disorder comorbidity, and will consist of an orientation session and 6 group treatment sessions. These participants will also receive substance abuse treatment as usual at a community Intensive Outpatient Program.
Treatment as usualParticipants in this arm receive the standard Intensive Outpatient treatment for their substance use disorder at a community addictions treatment facility.
Start Date: November 15, 2013
Completed Date: November 15, 2016
Primary Outcome: Brief Symptom Inventory
Secondary Outcome: urine toxicology screen
Study sponsors, principal investigator, and references
Principal Investigator: Kate B Taylor, Ph.D.
Lead Sponsor: University of California, Los Angeles