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Arthritis | Study of Arthritis and Related Conditions

Arthritis research study

What is the primary objective of this study?

This research protocol will recruit patients with arthritis and related conditions for the purpose of screening patients for treatment protocols, and evaluating the natural history of arthritis and related conditions. Patients will be evaluated clinically, radiographically and serologically, and standardized data will be uniformly collected on all patients. Additional imaging using sensitive MRI methods will be obtained in some patients. The collected blood and tissue will be utilized for laboratory studies to continue research on the pathogenic mechanisms of rheumatoid arthritis and related autoimmune joint diseases. Data from the history and physical examination as well as several disability questionnaires in the adult and pediatric population will be used to phenotypically characterize these patients and assess outcome and functional status. Any medical care recommended or provided to the patients will be consistent with routine standards of practice and provided in consultation with the patient's referring physician....

Who is eligible to participate?

- INCLUSION CRITERIA: No age limits. History of inflammatory synovitis of at least one or more swollen joints. Patient's ability and willingness to give informed consent or in the pediatric patients, the parent's willingness to give informed consent and the patient's willingness to assent to the protocol whenever possible. EXCLUSION CRITERIA: None if patients fulfill inclusion criteria.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Arthritis

Synovitis

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Study Status

Recruiting

Start Date: September 29, 2000

Completed Date:

Phase:

Type: Observational

Design:

Primary Outcome:

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: James D Katz, M.D.

Lead Sponsor: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborator:

More information:https://clinicaltrials.gov/show/NCT00006333

Lin JP, Cash JM, Doyle SZ, Peden S, Kanik K, Amos CI, Bale SJ, Wilder RL. Familial clustering of rheumatoid arthritis with other autoimmune diseases. Hum Genet. 1998 Oct;103(4):475-82.

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