Juvenile Idiopathic Arthritis | Magnetic Resonance Imaging Follow-up on Temporomandibular Arthritis in Children With Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis research study

What is the primary objective of this study?

Children with juvenile idiopathic arthritis (JIA) suffer in up to 87% of the cases of arthritis of the temporomandibular joints (TMJs). Magnetic resonance imaging (MRI) is the only modality for the early diagnosis of TMJ involvement. Aim of the study is to compare symptoms and clinical findings with MRI and ultrasonography results and to describe the action of the current medication on the arthritis of the TMJs.

Who is eligible to participate?

Inclusion Criteria: - Children with defined JIA. Exclusion Criteria: - Children without defined diagnosis of JIA.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Juvenile Idiopathic Arthritis

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Procedure:Steroid injection into the TMJs.In case of otherwise noncontrollable TMJ involvement steroids are injected into arthritic TMJs under MRI guidance.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Children with JIA

Study Status

Unknown status

Start Date: May 2008

Completed Date: June 2010


Type: Observational


Primary Outcome: TMJ arthritis on MRI

Secondary Outcome: TMJ arthritis on ultrasound

Study sponsors, principal investigator, and references

Principal Investigator: Nikolay Tzaribachev, MD

Lead Sponsor: University Hospital Tuebingen


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