Heart Failure | The Effects of the Inspiratory Muscle Plus Aerobic Training Compare to Aerobic Training Alone in Heart Failure Patients.
Heart Failure research study
What is the primary objective of this study?
This study aims to compare effects of inspiratory muscle training added by aerobic training to aerobic training alone in heart failure patients with inspiratory muscle weakness. To do so, strength and endurance of inspiratory muscles, functional capacity, quality of life, heart rate variability and sleep apnea evaluations will be conducted in patients with heart failure.
Who is eligible to participate?
Inclusion Criteria: - previous history of symptomatic heart failure caused by left ventricular systolic dysfunction - inspiratory muscle weakness (PImax < 70% of the predicted) - clinical stability, including no change in medications for the past three months Exclusion Criteria: - unstable angina - myocardial infarction, or cardiac surgery within the previous three months - chronic metabolic, orthopedic, or infectious diseases - treatments with steroids, hormones, or cancer chemotherapy - history of exercise-induced asthma, chronic obstructive pulmonary disease - smokers
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Other:Inspiratory muscle added by aerobic to aerobic aloneInspiratory muscle added by aerobic to aerobic alone
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
G2Inspiratory muscle training added by aerobic training to aerobic training alone
Start Date: March 2005
Completed Date: March 2010
Primary Outcome: To compare effects of inspiratory muscle training added by aerobic training to aerobic training alone in heart failure patients with inspiratory muscle weakness.
Secondary Outcome: To compare effects between the training groups evaluating strength and endurance of inspiratory muscles; functional capacity; the physical and psychological perceptions of quality of life and heart rate variability and sleep apnea.
Study sponsors, principal investigator, and references
Principal Investigator: Jorge P. Ribeiro, MD, ScD
Lead Sponsor: Hospital de Clinicas de Porto Alegre