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What is the primary objective of this study?

The association of cytokines with escitalopram has not been investigated in patients with major depressive disorder (MDD). Hence, the investigators will examine this association.

Who is eligible to participate?

Inclusion Criteria: 1. DSM-IV-defined Major depressive disorder, single episode 2. Age 20-65 3. Drug-naive 4. Hamilton Depression Rating Scale exceeding 14 scores Exclusion Criteria: 1. Major medical disorders 2. Substance use 3. Pregnant 4. Allergy to escitalopram

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Depression

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:Escitalopramescitalopram 10 mg/d to 20 mg/d

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

EscitalopramEscitalopram 10 mg/d to 20 mg/d

Study Status

Unknown status

Start Date: April 2012

Completed Date: April 2013

Phase: N/A

Type: Interventional

Design:

Primary Outcome: The changes in cytokines

Secondary Outcome: The changes in Hamilton Depression Rating Scale

Study sponsors, principal investigator, and references

Principal Investigator: Peishen Ho, M.D.

Lead Sponsor: Beitou Armed Forces Hospital, Taipei, Taiwan

Collaborator:

More information:https://clinicaltrials.gov/show/NCT01587326