Depression | The Effects of Escitalopram on Cytokines
Depression research study
What is the primary objective of this study?
The association of cytokines with escitalopram has not been investigated in patients with major depressive disorder (MDD). Hence, the investigators will examine this association.
Who is eligible to participate?
Inclusion Criteria: 1. DSM-IV-defined Major depressive disorder, single episode 2. Age 20-65 3. Drug-naive 4. Hamilton Depression Rating Scale exceeding 14 scores Exclusion Criteria: 1. Major medical disorders 2. Substance use 3. Pregnant 4. Allergy to escitalopram
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:Escitalopramescitalopram 10 mg/d to 20 mg/d
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
EscitalopramEscitalopram 10 mg/d to 20 mg/d
Start Date: April 2012
Completed Date: April 2013
Primary Outcome: The changes in cytokines
Secondary Outcome: The changes in Hamilton Depression Rating Scale
Study sponsors, principal investigator, and references
Principal Investigator: Peishen Ho, M.D.
Lead Sponsor: Beitou Armed Forces Hospital, Taipei, Taiwan