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Cellulitis | The Use of Oral Steroids in the Treatment of Cellulitis

Cellulitis research study

What is the primary objective of this study?

The prevalence of cellulitis in society is very high, as much as 3% of visits to Emergency Departments are for the treatment of this disease. The treatment of cellulitis varies depending on the severity. Low severity cases are treated with pain control and antibiotics by mouth and high severity are treated with antibiotics intravenously and pain control. The investigator's hypothesis is to see if the addition of steroids, which are known to decrease inflammation, will decrease the length of the disease process. If so, it will decrease the length of stay if IV antibiotics are needed, it will decrease duration of days out of work and decrease the overall pain control required and therefore patient satisfaction.

Who is eligible to participate?

Inclusion Criteria: - 18-70 years old - signs/symptoms of cellulitis Exclusion Criteria: - steroid use in last 2 weeks - hx of adrenal insufficiency - suspicion for dvt or abcess - systemic signs of sepsis - ICU admission

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Cellulitis

Erysipelas

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:PrednisonePrednisone, 60 mg, one time at time of diagnosis

Drug:Placebo Oral TabletPlacebo

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

PrednisoneUse of prednisone to decrease LOS and overall treatment time of cellulitis

Placebo

Study Status

Withdrawn

Start Date: January 15, 2010

Completed Date: August 31, 2010

Phase: Phase 2

Type: Interventional

Design:

Primary Outcome: Time to cellulitis resolving

Secondary Outcome: Length of stay

Study sponsors, principal investigator, and references

Principal Investigator: Scott Goldstein, DO

Lead Sponsor: Milton S. Hershey Medical Center

Collaborator:

More information:https://clinicaltrials.gov/show/NCT00893048

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