Other Reconstructive Surgery | Clonidine in Femoral Nerve Block Surgery in Children
Other Reconstructive Surgery research study
What is the primary objective of this study?
Knee arthroscopy is a common surgical procedure in pediatrics in which the knee joint is visualized through a small camera to help diagnose and treat knee problems. This procedure is commonly accomplished with the use of general anesthesia. Regional anesthesia is commonly completed with a single injection of local anesthetic around the femoral nerve to provide pain relief for several hours following knee arthroscopy. The intent of this study is to examine the effects of clonidine in addition to local anesthetics for femoral nerve blockade in providing children and adolescents post-operative analgesia. The investigators hypothesize the addition of low dose clonidine (1 mcg/kg) provides an additional 4 hours of post operative analgesia following arthroscopic knee surgery and reduces post-operative opiate requirement.
Who is eligible to participate?
Inclusion Criteria: - American Society of Anesthesiologist (ASA) functional status I or II - Patients scheduled for arthroscopic knee surgery only Exclusion Criteria: - Patients with history of chronic opioid therapy, central or peripheral neuropathy, contraindications to regional anesthesia, history of allergy to clonidine or ropivicaine, or anterior cruciate ligament reconstructive surgery in addition to knee arthroscopy
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Other Reconstructive Surgery
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:Ropivacaineropivacaine 0.2% 0.5 ml/kg (max 20 ml)
Drug:Clonidineclonidine 1 mcg/kg AND ropivacaine 0.2% 0.5 ml/kg (max 20 ml)
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Ropivacaine plus clonidineRopivacaine plus clonidine for femoral block
RopivacaineRopivacaine alone for femoral block
Start Date: April 2011
Completed Date: March 2013
Phase: Phase 2
Primary Outcome: Pain
Secondary Outcome: Heart rate
Study sponsors, principal investigator, and references
Principal Investigator: Amod Sawardekar, MD
Lead Sponsor: Nationwide Children's Hospital