Head Injury | Adjuvant Acupuncture for Severe Head Injury
Head Injury research study
What is the primary objective of this study?
The purpose of this study is to determine the therapeutic effect of acupuncture on severe head injury under conventional treatment. A double-blind clinical trial is conducted up to 6 weeks and the change of subjects' Glasgow coma scale (GCS) and muscle power is measured.
Who is eligible to participate?
Inclusion Criteria: - subjects aged 12 to 70 years with severe head injury (Glasgow coma scale score 8 or less) - with informed consent Exclusion Criteria: - dilated pupils without light reflex - serious complications during therapeutic course - interruption of therapeutic course - unfavored condition assessed by physician in charge - without informed consent
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Other:acupunctureacupuncture on GV26 and 12 Well points
Other:laser acupuncturelaser acupuncture on GV26 and 12 Well points
Other:controlsham laser acupuncture
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
acupunctureacupuncture on GV26 and 12 Well points
laser acupuncturelaser acupuncture on GV26 and 12 Well points
control grouplaser acupuncture without laser output in control group.
Start Date: January 2013
Completed Date: July 2015
Primary Outcome: Glasgow Coma Scale (GCS)
Secondary Outcome: Muscle Power (MP)
Study sponsors, principal investigator, and references
Principal Investigator: Wen-Long Hu, MS
Lead Sponsor: Chang Gung Memorial Hospital
DeFina PA, Fellus J, Thompson JW, Eller M, Moser RS, Frisina PG, Schatz P, Deluca J, Zigarelli-McNish M, Prestigiacomo CJ. Improving outcomes of severe disorders of consciousness. Restor Neurol Neurosci. 2010;28(6):769-80. doi: 10.3233/RNN-2010-0548.
Clauss R, Nel W. Drug induced arousal from the permanent vegetative state. NeuroRehabilitation. 2006;21(1):23-8.