Sudden Cardiac Death | Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk

Sudden Cardiac Death research study

What is the primary objective of this study?

Sudden cardiac death is a tragic event that strikes all age groups and is unfortunately increasing in prevalence. Because it is difficult to predict those at highest risk, this study is designed to test the hypothesis that new imaging techniques (magnetic resonance imaging [MRI] and computed tomography [CT]) are useful for identifying factors which put people at high risk for sudden death.

Who is eligible to participate?

Inclusion Criteria: - Left ventricular ejection fraction <45% - Planned implantable cardioverter-defibrillator (ICD) implantation for clinical indications (primary prevention) Exclusion Criteria: - History of sudden death (secondary prevention) - Contraindication to undergoing MRI (metallic implant, pacemaker, etc.)

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Sudden Cardiac Death

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Study Status


Start Date: October 2003

Completed Date: July 2020


Type: Observational


Primary Outcome: sudden cardiac death

Secondary Outcome: heart failure admission

Study sponsors, principal investigator, and references

Principal Investigator: Robert G. Weiss, MD

Lead Sponsor: Johns Hopkins University

Collaborator: Donald W. Reynolds Foundation

More information:

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