Cardiovascular Diseases | Epidemiology of Sudden Death in Cameroon

Cardiovascular Diseases research study

What is the primary objective of this study?

Background The burden of sudden death (SD) in sub-Saharan Africa is unknown. The aim is to assess the incidence, etiology and patient characteristics of SD in a sub-Saharan country. Methods The Douala-SD study is a prospective, multicenter, community-based registry monitoring all cases of SD occurring in index areas of Douala city. Investigators will use the definition of SD as natural death occurring within 24h at the onset of symptoms. Demographic, clinical, electrocardiographic and biological variables (when available) of victims will be recorded. All deaths occurring in residents of health areas of interest will be checked for past medical history, circumstances of death, and autopsy (if possible). Conclusion This maiden Douala-SD study will provide comprehensive, contemporary data on the epidemiology of SD in a sub-Saharan African country and will help in the development of strategies to prevent and manage SD in Africa.

Who is eligible to participate?

Inclusion Criteria: All witnessed and unwitnessed victims of unexpected natural death Exclusion Criteria: - Victims living in the area of interest for a short time frame (< 12 months) - Absence of information helping to determine circumstances of death

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Cardiovascular Diseases

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Resident of health areas of interestResidents of 4 health areas will be monitored for sudden unexpected death within 72 months of follow up. Circumstances and past medical conditions will be checked.

Study Status

Unknown status

Start Date: January 2014

Completed Date: December 2016


Type: Observational [Patient Registry]


Primary Outcome: Sudden death, either cardiac or non-cardiac origin

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Aimé BONNY, MD

Lead Sponsor: Cameroon Resuscitation Council

Collaborator: ARCV

More information:

Arthur JT. Sudden deaths: cardiac and non-cardiac in children in Accra. West Afr J Med. 1995 Apr-Jun;14(2):108-11.

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