Delirium | Validating a Delirium Prediction Model for Critically Ill Patients

Delirium research study

What is the primary objective of this study?

The objective of this study is to determine the incidence of delirium in adults patients who are admitted at the critical care unit of a Dutch University Hospital with the mapping of relevant delirium risk factors The primary aim is to validate the investigators' developed delirium prediction model for critical care patients. A secondary aim is to find differences between delirious patients and non-delirious patients on different aspects of diagnostics, treatment and care, outcome, length of stay, and inflammation. According to Dutch law, the need to obtain informed consent was waived by the Committee on Research Involving Human Subjects (CMO) of Nijmegen for this observational study (2007/283).

Who is eligible to participate?

Inclusion Criteria: - all adult patients (18 years and older) admitted at the critical care unit of our hospital Exclusion Criteria: - admitted < 12 hours on ICU - not able to understand Dutch - patients with serious hearing and visibility disabilities - mentally retarded patients - patients suffering from receptive aphasia - delirious before admission

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

delirious patientsminimal any positive CAM-ICU score during ICU admission

non-delirious patientswithout any positive CAM-ICU score during ICU admission

Study Status

Unknown status

Start Date: May 2009

Completed Date: October 2009


Type: Observational


Primary Outcome: delirium

Secondary Outcome: markers of inflammation

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: Radboud University


More information:

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