Depression | Bending Adolescent Depression Trajectories Through Personalized Prevention

Depression research study

What is the primary objective of this study?

Investigators will combine risk factor research and evidence-based prevention programs, to advance knowledge on personalized approaches to prevention that may be able to better \"bend trajectories\" of depression that surge throughout adolescence.

Who is eligible to participate?

Inclusion Criteria: - Currently in the 6th to 11th grades - Adolescent and parent must be English-speaking - Parental consent and adolescent consent Exclusion Criteria: - Presence of current Major Depressive Disorder, dysthymia, bipolar disorder, or significant psychosis - Suicide attempt in the past week or significant suicidal ideation in the past week - Presence of significant psychopathology or significant pervasive developmental delays that would make the group inappropriate

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Behavioral:Interpersonal Psychotherapy- Adolescent Skills TrainingA group prevention program that includes a 60-minute pre-group session, 8 weekly 90-minute group sessions, a 60-minute mid-group session, and 3 60-minute booster sessions. IPT-AST focuses on psychoeducation and interpersonal skill-building to decrease interpersonal conflict and increase interpersonal support and competence.

Behavioral:Coping with StressA group prevention program that consists of 8 acute 90-minute group sessions, 2 parent group sessions, and 3 continuation sessions lasting 60 minutes each. Participants are taught to apply cognitive techniques to their personal thoughts, with the goal of generating effective counterarguments to unrealistic negative beliefs.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Interpersonal Psychotherapy- Adolescent Skills TrainingInterpersonal Psychotherapy- Adolescent Skills Training

Coping with StressCoping with Stress

Study Status

Active, not recruiting

Start Date: September 2013

Completed Date: August 2019

Phase: N/A

Type: Interventional


Primary Outcome: Presence of a Major Depressive Episode or Dysthymia on the Schedule for Affective Disorders for School Aged Children - Present and Life Time Version (K-SADS-PL)

Secondary Outcome: Children's Depression Inventory (CDI)

Study sponsors, principal investigator, and references

Principal Investigator: Jami F Young, Ph.D.

Lead Sponsor: Children's Hospital of Philadelphia

Collaborator: National Institute of Mental Health (NIMH)

More information:

Discuss Depression