Fatigue | Biomarkers of Fatigue Related to Adjuvant Chemotherapy for Breast Cancer
Fatigue research study
What is the primary objective of this study?
Fatigue is common in cancer patients receiving adjuvant chemotherapy. To further understand the mechanism of fatigue and search for potential biomarkers, we will conduct a prospective study with breast cancer patients receiving adjuvant chemotherapy.
Who is eligible to participate?
Inclusion Criteria: - Non metastatic breast cancer; - Patients undergoing adjuvant chemotherapy Exclusion Criteria: - hypothyroidism; - Depression; - anemia; - heart disease or decompensated hypertension
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Control: patients without fatiguePatients whose scores on the brief fatigue inventory (BFI) (15) won't increase after having received the first cycle of chemotherapy will be considered as controls
Patients with fatighePatients whose scores on the brief fatigue inventory (BFI) (15) increase after having received the first cycle of chemotherapy will be considered as having manifested fatigue
Start Date: November 2013
Completed Date: March 2014
Primary Outcome: Potential biomarkers related to chemotherapy induced fatigue
Study sponsors, principal investigator, and references
Principal Investigator: Felipe M Cruz, PhD
Lead Sponsor: Faculdade de Medicina do ABC