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Morbid Obesity | Probiotics Improve Gastrointestinal Symptoms After Roux-en-Y Gastric Bypass: A Prospective Randomized Trial

Morbid Obesity research study

What is the primary objective of this study?

Obesity has been a global epidemic. Currently, bariatric surgery has been recognized as the only successful treatment for morbid obesity. Laparoscopic gastric bypass (LGB) is the leading bariatric surgery worldwide including Taiwan, it's resulted in significant weight loss and resolution of metabolic co-morbidities in morbidly obese patients . However, annoyed Gastro-Intestinal (GI) symptoms are a common complaint after gastric bypass like foul smell flatus, oil flatus and over flatus. The aim of this study was to determine whether probiotics would improve annoyed GI symptoms after gastric bypass. Probiotics are live microorganisms (in most cases, bacteria) that are similar to beneficial microorganisms found in the human gut. They are also called \"friendly bacteria\" or \"good bacteria.\" Probiotics are available to consumers mainly in the form of dietary supplements and foods.

Who is eligible to participate?

Inclusion Criteria: - morbid obesity patients after gastric bypass with annoyed intestinal symptoms Exclusion Criteria: - cannot obey the orders to take medicine

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Morbid Obesity

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Dietary Supplement:probiotics,digestive enzymepatients was randomized into 3 groups: clostridium butyricum MIYAIRI group (80 mg daily) bifidobacterium Longum BB536 group (2 packs daily) biotase:4 tables per day

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

probiotic, lifestyle counseling

Study Status

Unknown status

Start Date: October 2011

Completed Date: July 2012

Phase: N/A

Type: Interventional

Design:

Primary Outcome: Questionnaire of gastrointestinal quality of life

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: YAO W C, Phd

Lead Sponsor: Min-Sheng General Hospital

Collaborator:

More information:https://clinicaltrials.gov/show/NCT01431651

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