Ilues | Influence of Coffee Intake on Postoperative Bowel Function After Comprehensive Staging Surgery for Gynecological Malignancies: A Randomized Controlled Trial.

Ilues research study

What is the primary objective of this study?

A delay in the return of normal bowel function with the passage of flatus and feces is one of the most important factors affecting early recovery and discharge in patients undergoing open complete staging surgery for gynecological malignancies. A prolonged hospital stay increases the risk of hospital-acquired infections, deep vein thrombosis, pulmonary compromise and total hospital costs. The aim of this study was to assess the effectiveness of coffee intake on postoperative bowel function in patients undergoing abdominal complete staging surgery for gynecological malignancies.

Who is eligible to participate?

Inclusion Criteria: - Female patients preparing for complete surgical staging for malignant gynecologic disease such as endometrial cancer, cervix cancer and ovarian cancerwere assessed for eligibility. Exclusion Criteria: Exclusion criteria for the study - included thyroid diseases, - inflammatory bowel disease, - complaints of chronic constipation (defined as two or fewer bowel movements per week), - a history of prior abdominal bowel surgery, abdominal radiation, neoadjuvant chemotherapy, - need for intensive care more that 24 hpostoperatively, - nasogastric tube drainage beyond the first postoperative morning, - bowel anastomosis and upper abdominalmultivisceral surgical approaches in relation to the debulking surgery.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Dietary Supplement:caffe

Dietary Supplement:Water

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.


water groupwater

Study Status


Start Date: November 2013

Completed Date: February 2016

Phase: N/A

Type: Interventional


Primary Outcome: time to first flatus

Secondary Outcome: time to tolerance diet

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: Erzincan Military Hospital


More information:

Discuss Flatulence