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Postoperative Ileus | Role of Chewing Gum in Reducing Post Operative Ileus After Reversal of Ileostomy

Postoperative Ileus research study

What is the primary objective of this study?

Postoperative ileus is generally referred to as the transient impairment of bowel motility after abdominal or other surgery and diagnosed by postoperative abdominal pain vomiting constipation and distension. The potential complications of prolonged POI include increased postoperative pain, increased nausea and vomiting, pulmonary complications, poor wound healing, delay in resuming oral intake, delay in postoperative mobilization, prolonged hospitalization, and increased health-care costs. The estimated economic impact of POI in the United States is $7.5 billion per year, excluding the expenses of work loss. In view of these complications and economic burden a number of pharmacologic and non-pharmacologic strategies have been adopted by the doctors all over the world to reduce the burden of postoperative ileus.These programs involve transverse or curved surgical incisions, removal of nasogastric tubes at the end of anesthesia, intraoperative and postoperative analgesia, early postoperative feeding, mobilization, and gum chewing. The use of gum chewing has emerged as a new and simple modality for decreasing POI. And reviews have concluded that there is consistent benefit for patients from gum chewing after the intestinal surgery; colonic surgery and gynecological surgery. This study is based on the hypothesis that postoperative gum chewing is beneficial in prevention of postoperative ileus after reversal of ileostomy.

Who is eligible to participate?

Inclusion Criteria: 1. Patients of either gender with age ranging from 15 to 60 years. 2. Patients whose ileostomies were made for typhoid or tuberculous perforation 3. Patients with no distal obstruction on loopogram. Exclusion Criteria: - 1. Patients with age less than 15 years and greater than 60. 2. Patients having co-morbid factors such as diabetes and ischemic heart disease. 3. Patients whose ileostomy was made for any condition other than typhoid or tuberculosis.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Postoperative Ileus

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Other:Sugar Free Chewing Gum'Extra' sugar free gum will be used as an intervention. Patients will be required to chew a gum for 30 min at intervals of 6 hours for first 48 hours post operatively or until they pass flatus.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Sugar Free Chewing GumAll patients receiving sugar free gum

ControlPatients receiving no intervention

Study Status

Completed

Start Date: June 2014

Completed Date: December 2015

Phase: N/A

Type: Interventional

Design:

Primary Outcome: passage of flatus

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Mahmood Ayyaz, FCPS FACS

Lead Sponsor: Services Hospital, Lahore

Collaborator:

More information:https://clinicaltrials.gov/show/NCT02155153

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