Glaucoma | Steroids After Laser Trabeculoplasty for Glaucoma
Glaucoma research study
What is the primary objective of this study?
The purpose of this study is to determine whether the choice of post-operative eye drop administered after selective laser trabeculoplasty (SLT) for glaucoma affects the efficacy in lowering intraocular pressure (IOP).
Who is eligible to participate?
Inclusion Criteria: - clinical diagnosis of glaucoma - clinician has determined that SLT laser is indicated - IOP currently >18 and was ever >21 in the past (e.g. prior to treatment) Exclusion Criteria: - prior history of uveitis - prior glaucoma surgery including glaucoma laser surgery - pregnant or 3 months post-partum
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:Prednisolone 1%Prednisolone 1% to lasered eye 4 times/day for 4.5 days
Drug:KetorolacKetorolac 0.5% to lasered eye 4 times/day for 4.5 days
Drug:Artificial TearsArtificial saline tears to lasered eye 4 times/day for 4.5 days
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Artificial TearsTopical artificial tears dosed 4 times per day for 4 days in treated eye after laser trabeculoplasty.
Non-steroidal anti-inflammatoryTopical ketorolac 0.5% dosed 4 times per day for 4 days in treated eye after laser trabeculoplasty.
SteroidTopical prednisolone 1% dosed 4 times per day for 4 days in treated eye after laser trabeculoplasty.
Start Date: September 2009
Completed Date: September 2015
Phase: Phase 4
Primary Outcome: Intraocular Pressure (IOP) Change
Secondary Outcome: Intraocular Inflammation
Study sponsors, principal investigator, and references
Principal Investigator: Jeffrey L Goldberg, MD, PhD
Lead Sponsor: Stanford University
Collaborator: Bascom Palmer Eye Institute