Auditory Verbal Hallucinations | Non-invasive Brain Stimulation for Auditory Verbal Hallucinations in Schizophrenia

Auditory Verbal Hallucinations research study

What is the primary objective of this study?

The current study investigates the basic principles that underlie the efficacy of transcranial direct current stimulation for chronic auditory verbal hallucinations in schizophrenia in a multimodal design.

Who is eligible to participate?

Inclusion Criteria: - diagnosis of schizophrenia - chronic auditory verbal hallucinations - right-handed Exclusion Criteria: - drug abuse other than nicotine - severe cognitive deficits - severe medical conditions - severe neurological disorders - severe microangiopathy - history of electroconvulsive therapy - pregnancy or lactation

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Auditory Verbal Hallucinations


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Device:tDCSactive vs. sham tDCS left hemisphere

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

verum tDCSleft-hemispheric tDCS: anode placed midway between F3 and FP1, cathode placed midway between T3 and P3

sham tDCSleft-hemispheric sham tDCS: anode placed midway between F3 and FP1, cathode placed midway between T3 and P3

Study Status


Start Date: March 2013

Completed Date: December 2015

Phase: N/A

Type: Interventional


Primary Outcome: Change of Auditory Hallucination Rating Scale score

Secondary Outcome: Positive And Negative Syndrome Scale

Study sponsors, principal investigator, and references

Principal Investigator: Robert Lindenberg, MD

Lead Sponsor: Charite University, Berlin, Germany


More information:

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