Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:simvastatinmedication with simvastation on the dosage of 40mg per day before the operation and all the time after the operation
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
1simvastatin groupbefore the operation, the patient start the simvastatin medication on the dosage of 40mg per day
2contral groupjust do routin operation with no use of simvastatin, other medication is exact the same as the simvastatin group
Start Date: January 2009
Completed Date: January 2012
Phase: Phase 1
Primary Outcome: the simvastatin can alleviate pulmonary hypertension
Secondary Outcome: simvastatin can highten the perioperative and long term survaval rate and the living quality
Study sponsors, principal investigator, and references
Principal Investigator: Huili Gan, MD,Ph.D.
Lead Sponsor: Capital Medical University