Hyponatremia | Establishment of an Algorithm for a Clinical Classfication of Hypoosmolar Hyponatremia
Hyponatremia research study
What is the primary objective of this study?
The prospective clinical diagnosis of hyponatremia is often very difficult- but requirement
for an appropriate and riskless treatment of hyponatremia. This study try to establish an
algorithm handling a prospective clinical categorization of hyponatremia and approving
together the start of an appropriate symptomatic therapy.
Who is eligible to participate?
- hypoosmolar hyponatremia with serum sodium concentration ≤129 mmol/l and serum
osmolality ≤ 280 mosm/kg;
- age > 18 years;
- letter of agreement.
- gravidity and lactation;
- restricted decision-making-ability
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Start Date: April 2007
Completed Date: December 2008
Primary Outcome: Establishment of an clinical algorithm to differentiate the different causes of hyponatremia
Study sponsors, principal investigator, and references
Principal Investigator: Bruno Allolio, MD
Lead Sponsor: University of Wuerzburg