Hyponatremia | Hyponatremia and Myometrium Contractility. An Invitro Study

Hyponatremia research study

What is the primary objective of this study?

Hyponatremia during labour has been associated with prolonged labour, and increased incidence of instrumental delivery and emergency caesarean section. Sodium influx in myometral cells are involved in contractility,and and influence of hyponatraemia on contractility can be suspected.

Who is eligible to participate?

Inclusion Criteria: - Singleton pregnancy at term Exclusion Criteria: - Preeclampsia

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Study Status


Start Date: October 2012

Completed Date: October 2015


Type: Observational


Primary Outcome: Contractility

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Gunvor Ekman-Ordeberg, PhD

Lead Sponsor: Karolinska University Hospital


More information:

Moen V, Brudin L, Rundgren M, Irestedt L. Hyponatremia complicating labour--rare or unrecognised? A prospective observational study. BJOG. 2009 Mar;116(4):552-61. doi: 10.1111/j.1471-0528.2008.02063.x. Epub 2009 Jan 27.

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