Hyponatremia | Bioimpedance Spectroscopy for the Differential Diagnosis of Hyponatremia

Hyponatremia research study

What is the primary objective of this study?

We aimed to investigate the role of bioimpedance spectroscopy for the diagnosis of hyponatremia

Who is eligible to participate?

Inclusion Criteria: - Willing to participate in the study with written informed consent - Older than 18-years Exclusion Criteria: - The presence of pacemaker or defibrillator - Artificial joints, pin or amputation - Pregnancy or lactating.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Hypovolemic hyponatremiaNegative values of "Overhydration" measured by Bioimpedance spectroscopy

Hypervolemic hyponatremiaPositive values of "Overhydration" measured by Bioimpedance spectroscopy

Study Status


Start Date: February 2013

Completed Date: September 2013


Type: Observational [Patient Registry]


Primary Outcome: Accuracy of volume status measured by bioimpedance spectroscopy

Secondary Outcome: Laboratory data and echocardiography

Study sponsors, principal investigator, and references

Principal Investigator: Ender Hur, Assoc.Prof.

Lead Sponsor: Zonguldak Karaelmas University


More information:

Hur E, Usta M, Toz H, Asci G, Wabel P, Kahvecioglu S, Kayikcioglu M, Demirci MS, Ozkahya M, Duman S, Ok E. Effect of fluid management guided by bioimpedance spectroscopy on cardiovascular parameters in hemodialysis patients: a randomized controlled trial. Am J Kidney Dis. 2013 Jun;61(6):957-65. doi: 10.1053/j.ajkd.2012.12.017. Epub 2013 Feb 15.

Discuss Hyponatraemia