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Hyponatremia | Characterisation of Neuropsychological and Motoric Performance in Patients With Hyponatremia

Hyponatremia research study

What is the primary objective of this study?

The aim of this epidemiological study is to characterize the neuropsychological and motoric performance in patients with hyponatremia. Newer studies revealed an association between mild hyponatremia and unstable walking, frequency of falls and risk of a fracture, questioning the paradigm of an \"asymptomatic\" hyponatremia. Until now, there is no known detailed investigation and characterisation of the cognitive and motoric performance or limitation by this disorder. Therefore this study will investigate patients with hyponatremia on the basis of neuropsychological and neurological tests.

Who is eligible to participate?

Inclusion Criteria: - Men and women 18 years of age or older - Hyponatremia with serum sodium < 130 mmol/l Exclusion Criteria: - traumatic cerebral injury, hemorrhagic and ischemic insult as cause of hyponatremia - professional or private relationship between subject and the investigators, or dependance on the investigators - Placement in an institution based on official orders - Patients who are unable to give informed consent

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Hyponatremia

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Other:Neuropsychological and motoric testsEvaluation before and after therapy of hyponatremia Neuropsychological tests Mini Mental Status Test Dem-Tect Rey-Osterrieth Complex Figure Test Trailmaking Test Beck Depression Inventory d2-R (optional) Motoric tests modified UPDRS (Unified Parkinson Disease Rating Scale) Part III Timed-up-and-go Test Halstead Fingertapping Test AIMS (Abnormal involuntary movement scale) EEG

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Neuropsychological and motoric testsNeuropsychological and motoric tests are conducted.

Study Status

Recruiting

Start Date: June 2012

Completed Date: December 2018

Phase: N/A

Type: Interventional

Design:

Primary Outcome: Assessment of Performance in individual tests

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Volker Burst, MD

Lead Sponsor: University of Cologne

Collaborator:

More information:https://clinicaltrials.gov/show/NCT01879774

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