Irritable Bowel Syndrome | Delivered Dietary Intervention for Children With Irritable Bowel Syndrome
Irritable Bowel Syndrome research study
What is the primary objective of this study?
The purpose of this study is to determine whether a specific diet may help children with irritable bowel syndrome.
Who is eligible to participate?
Inclusion Criteria: Must include all of the following: 1. Children between the ages of 7-17 years; 2. Meet the criteria for IBS based on the Questionnaire on Pediatric Gastrointestinal Symptoms Rome III Version, including pain/discomfort a minimum of twice per week; 3. Negative physician evaluation for an organic etiology of the pain within the past year Exclusion Criteria: Will include any of the following: 1. Diabetes or other disease process requiring specialized dietary management; 2. Malnutrition or obesity (BMI >95%); 3. Inability to eat by mouth; 4. Antibiotic or medicinal probiotic usage within the past 3 months (excluding yogurt); 5. Neuromodulator (e.g. amitriptyline) usage within the past 3 months 6. Start of, or change in gastrointestinal medication (e.g. laxative) dose that may cause or ameliorate abdominal symptoms within the past month
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Irritable Bowel Syndrome
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Other:Low fermentable substrate dietDiet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols.
Other:High fermentable substrate dietDiet high in fermentable oligosaccharides, disaccharides, monosaccharides and polyols
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
High fermentable substrate dietHigh fermentable substrate diet provided for two days
Low fermentable substrate dietLow fermentable substrate diet provided for two days
Start Date: January 2011
Completed Date: December 2017
Primary Outcome: Average daily abdominal pain frequency
Secondary Outcome: Abdominal pain severity
Study sponsors, principal investigator, and references
Principal Investigator: Bruno P Chumpitazi, MD, MPH
Lead Sponsor: Baylor College of Medicine
Collaborator: NASPGHAN Foundation