PatientsVille.com LogoPatientsVille.com

Heart Failure | Is There a Benefit to Optimize Heart Failure (HF) Treatment in Aged Over 80 Year's Old Patients?

Heart Failure research study

What is the primary objective of this study?

The purpose of this study is to determine if there is an interest to optimize HF (heart failure) management in patients over 80 years old. The primary objective is to assess the effect of HF (heart failure) optimized management (guidelines of the European society of Cardiology (ESC) on Quality of Life (QOL) in aged over 80 year's old at 6 months.

Who is eligible to participate?

Inclusion Criteria: - Aged over 80 year's old subjects - Hospitalized for an acute heart failure - Left Ventricle Ejection Fraction ≤ 35% - Evaluated life expectancy (Seattle HF score) > 1 year Exclusion Criteria: - Dementia - Does not understand French language - Followed with an optimized management - With reduced mobility - Recruited in another clinical trial or in a HF management network - AHF with curable aetiology : cardiovascular surgery for CABG or valvular replacement, angioplasty - MDRD < 30 ml/min/1.73m²

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Heart Failure

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:- Angiotensin conversing enzyme inhibitors: enalapril, captopril, lisinopril, ramipril, trandolapril.The purpose of this study is to determine if there is an interest to optimize HF management in patients over 80 years old. The primary objective is to assess the effect of HF optimized management (guidelines of the European society of Cardiology (ESC) on QOL in aged over 80 year's old at 6 months

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

optimizedThe purpose of this study is to determine if there is an interest to optimize HF management in patients over 80 years old. The primary objective is to assess the effect of HF optimized management (guidelines of the European society of Cardiology (ESC) on QOL in aged over 80 year's old at 6 months

usual care

Study Status

Completed

Start Date: August 2011

Completed Date: June 2014

Phase: Phase 3

Type: Interventional

Design:

Primary Outcome: Change from baseline in quality of life

Secondary Outcome: Mortality

Study sponsors, principal investigator, and references

Principal Investigator: Romain ESCHALIER

Lead Sponsor: University Hospital, Clermont-Ferrand

Collaborator: Servier

More information:https://clinicaltrials.gov/show/NCT01437371

Discuss Lisinopril