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Drug Absorption | Influence of CPB and Mini CPB to the Absorption of the Metoprolol

Drug Absorption research study

What is the primary objective of this study?

Influence of perfusion, miniperfusion and off pump coronary artery bypass grafting to the absorbtion of metoprolol postoperatively, hypothesis in that miniperfusion and off pump surgery does not decrease absorbtion of the metoprolol compared to conventional pefusion.

Who is eligible to participate?

Inclusion Criteria: elective CABG patient - Exclusion Criteria: contraindication to metoprolol -

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Drug Absorption

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:blood concentration of metoprololmeasure blood concentration of metoprolol

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

blood concentration of metoprololhow does off-pump miniperfusion and perfusion CABG influence the absorption of metoprolol after CABG

Study Status

Unknown status

Start Date: November 2012

Completed Date: December 2015

Phase: N/A

Type: Interventional

Design:

Primary Outcome: absorbtion of the metoprolol

Secondary Outcome: atrial fibrillation

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: Kuopio University Hospital

Collaborator:

More information:https://clinicaltrials.gov/show/NCT01728272

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