Critically Ill Patients | Observational Prospective Study of the Predicted Value of Immature Thrombocytes Counts in Three Different Groups of Critically Ill Patients
Critically Ill Patients research study
What is the primary objective of this study?
Immature Platelet Fraction (IPF) is a new value in CBC blood tests Recent Studies showed that this value may be another prognostic factor in critically ill patients such as those admitted to ICU, or those with neutropenic Fever. The purpose of the study is to check if the IPF may be used as a prognostic Factor in these patients
Who is eligible to participate?
Inclusion Criteria: - Admission to hospital blood sample is taken between 24:00 pm till 15:00 pm Exclusion Criteria: - blood sample is taken after 15:00 pm in the first day of admission during the week - blood sample is taken on weekend: thursday 15:00 pm till saturday 24:00 pm
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Critically Ill Patients
Neutropenic Fever Patients
Patients With Hip Fractures
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Other:Immature Platelet Fraction
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Critically ill patients admitted to ICUthose patients who are admitted to ICU with multiorgan failure/injury
Neutropinc Fever patientsadmitted to ER, haemato-oncology or oncology
Patients of Hip's Fractureadmitted to orthopedic departement
Start Date: January 2014
Completed Date: November 2014
Type: Observational [Patient Registry]
Primary Outcome: Time to recovery from sepsis or time to death
Secondary Outcome: Predicting value of IPF for prognosis
Study sponsors, principal investigator, and references
Lead Sponsor: Dr. Yishai Ofran
Di Mario A, Garzia M, Leone F, Arcangeli A, Pagano L, Zini G. Immature platelet fraction (IPF) in hospitalized patients with neutrophilia and suspected bacterial infection. J Infect. 2009 Sep;59(3):201-6. doi: 10.1016/j.jinf.2009.07.007. Epub 2009 Jul 18.
De Blasi RA, Cardelli P, Costante A, Sandri M, Mercieri M, Arcioni R. Immature platelet fraction in predicting sepsis in critically ill patients. Intensive Care Med. 2013 Apr;39(4):636-43. doi: 10.1007/s00134-012-2725-7. Epub 2012 Oct 24.