Adverse Drug Event | The Effect of a Pharmacist Home Visit on Drug-related Problems Post-discharge.
Adverse Drug Event research study
What is the primary objective of this study?
the purpose of this study is to determine the the effect of a home-based medication management program on drug-related problems post-discharge.
Who is eligible to participate?
Inclusion Criteria: - patient uses more than three prescribed systemic drugs intended for chronic use at admission and discharge - patient has an expected length of stay of 48 hours or longer Exclusion Criteria: - Patients admitted for scheduled chemotherapy - Patients admitted for radiation therapy - Patients admitted for transplantation - Patients transferred from another hospital - Patients transferred from another non-eligible ward within the same hospital - No informed consent signed - A live expectancy less than 6 months - Inability to be counselled (e.g. cognitive dysfunction, language constraints who cannot be solved with an interpreter) - Discharge to a nursing home (presuming dependence on medication administration) - If patients' community pharmacy is not participating in this study
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Adverse Drug Event
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Behavioral:HomeCoMe-programA home visit by patients own community pharmacist within seven days after hospital discharge. The community pharmacist will perform a semi-structured interview on (1) use of the prescribed medication, (2) ADEs, (3) adherence issues, by (A) assessing patient's needs and concerns around his pharmacotherapy, (B) identifying and solving obstacles for medicines intake, (C) checking on the need for a compliance aid, (D) collecting spare medication and finally (4) knowledge on medication use, when to take which medicine and why, and medication changes made during the hospitalisation.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
HomeCoMe-program groupthe arm receiving the pharmacist home visit
Start Date: November 2013
Completed Date: February 2016
Primary Outcome: Identifying and solving adverse drug events (ADEs) and other drug-related problems (DRPs) post-discharge
Secondary Outcome: Improvement of adherence to medication at hospital discharge
Study sponsors, principal investigator, and references
Principal Investigator: Marcel L Bouvy, Prof, PharmD, PhD
Lead Sponsor: H.T. Ensing, PharmD, MSc
Collaborator: Zorggroep Almere
Schnipper JL, Kirwin JL, Cotugno MC, Wahlstrom SA, Brown BA, Tarvin E, Kachalia A, Horng M, Roy CL, McKean SC, Bates DW. Role of pharmacist counseling in preventing adverse drug events after hospitalization. Arch Intern Med. 2006 Mar 13;166(5):565-71.