PatientsVille.com LogoPatientsVille.com

Nausea | Inhalation Intervention for Nausea in the Emergency Department

Nausea research study

What is the primary objective of this study?

Randomized controlled trial comparing inhalation of isopropyl alcohol vs placebo (normal saline) pads to treat nausea in emergency department patients.

Who is eligible to participate?

Inclusion Criteria: - age range of 18-65 years of age - complaint of nausea and or vomiting - ability to breathe through nose - ability to read and write English Exclusion Criteria: - allergy to isopropyl alcohol - pregnancy or pregnancy status unknown to subject. Pregnancy test only if part of clinical course. - recent upper respiratory infection - recent intake of cefoperazone, disulfiram, or metronidazole or any other medications that are known produce nausea when exposed to alcohol. - use of antiemetic or psychoactive drug within 24 hours - alcohol abuse - nicotine within last 4 hrs

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Nausea

Vomiting

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Other:Alcohol prep pad groupSubjects inhale scent of alcohol pad

Other:Normal Saline prep padSubjects inhale scent of placebo (normal saline) pads

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Alcohol prep pad groupisopropyl alcohol prep pad

Normal Saline prep padnormal saline prep pad

Study Status

Completed

Start Date: April 2014

Completed Date: June 2015

Phase: N/A

Type: Interventional

Design:

Primary Outcome: Nausea Verbal Numerical Rating Scale (0-10) at 10 Minutes Post Intervention

Secondary Outcome: Verbal Numerical Rating Scale Pain Score (0-10) at 10 Minutes Post Intervention

Study sponsors, principal investigator, and references

Principal Investigator: Kenneth L Beadle, MPAS, BS

Lead Sponsor: Brooke Army Medical Center

Collaborator:

More information:https://clinicaltrials.gov/show/NCT02092441

Burleigh-Flayer HD, Gill MW, Strother DE, Masten LW, McKee RH, Tyler TR, Gardiner T. Isopropanol 13-week vapor inhalation study in rats and mice with neurotoxicity evaluation in rats. Fundam Appl Toxicol. 1994 Oct;23(3):421-8.

Discuss Nauseas