Intraocular Pressure | The Intraocular Pressure Measured by Different Tonometers in Corneal Edema

Intraocular Pressure research study

What is the primary objective of this study?

The investigators conduct this study to access the effect of corneal edema (the investigators are particularly interested in those who have the clinical central corneal edema) on the variation of intraocular pressure values measured by 3 commercial-available tonometers compare to the current gold standard tonometer; Goldmann applanation tonometer.

Who is eligible to participate?

Inclusion Criteria: - Age more than 18 year-old - Patients who have a clinical central corneal edema after clear cornea phacoemulsification and intraocular lens implantation - Agree to participate in the study and willing to sign an informed consent Exclusion Criteria: - Combined phacoemulsification and trabeculectomy - Clear cornea phacoemulsification that has suture on the cornea - Previous history of intraocular surgery, ocular trauma prior to phacoemulsification - Vitrectomized eye - History of glaucoma or ocular hypertension or using IOP lowering medication - History of diabetic retinopathy staged as severe non-proliferative or worse - Pregnant or breast-feeding women - History of refractive surgery or any keratoplastic procedure - Corneal opacities or diseases making no suitable tonometry - Severe dry eye syndrome - Wears contact lenses - Astigmatism higher than 2.5 diopters - Microphthalmos or buphthalmos - Subjects with having poor or eccentric fixation or nystagmus - Excessive eye squeezing - Known allergy to topical anesthesia - Known allergy to fluorescein solution

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Intraocular Pressure

Corneal Edema

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Other:Intraocular pressure measurementUsing different tonometers for intraocular pressure measurement

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Corneal edemaIntraocular pressure measurement

Study Status


Start Date: November 2013

Completed Date: June 2016


Type: Observational


Primary Outcome: Intraocular pressure

Secondary Outcome: Relationship between the central corneal thickness and intraocular pressure measured by each tonometer

Study sponsors, principal investigator, and references

Principal Investigator: Weerawat Kiddee, MD

Lead Sponsor: Prince of Songkla University


More information:

Discuss Oedema