Overdose | Monitoring of Overdose Patients With and Without Supplemental Oxygen in the Emergency Department

Overdose research study

What is the primary objective of this study?

This study will compare the data from pulse oximeters to capnographers as they are used to monitor patients who are being observed in the Emergency Department for a suspected overdose of alcohol or other drugs. The investigators will compare monitor data from patients who are and are not on supplemental oxygen, the ability of the monitors to predict the occurrence of airway interventions, and to detect ventilator changes noted on the opposing monitor. There will not be any interventions during this study other than the collection of data from the monitors and observation of the care of patients.

Who is eligible to participate?

Inclusion Criteria: - Airway is being monitored as a result of overdose Exclusion Criteria: - Under 18 years old - Unable to give informed consent at baseline - Prisoners

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.


Study Status


Start Date: May 2010

Completed Date: December 2013


Type: Observational


Primary Outcome: Airway Interventions Performed by ED Staff

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: James R Miner, MD

Lead Sponsor: Hennepin Healthcare Research Institute.


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