Throat Pain | The Effectiveness of Probiotics for the Therapy of Acute Pharyngotonsillitis in Adult Patients

Throat Pain research study

What is the primary objective of this study?

The addition of probiotics to the routine therapy of Acute Pharyngotonsillitis in adult patients may shorten the duration, and reduce the severity of the disease.

Who is eligible to participate?

Inclusion Criteria: - Age over 18 years - Acute pharyngotonsillitis for which hospitalization for intravenous antibiotic treatment and/or fluids is needed Exclusion Criteria: - Current therapy with systemic prednisone or equivalent at 20 mg/d for more than 10 days prior to inclusion

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Throat Pain

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:Placebo1 tablet 2 times daily

Drug:Probiotics1 tablet twice daily

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Penicillin Ghospitalization of 30 patients given penicilline intraveniously for 72 hours

Placebo30 hospitalized patients will be given placebo with a regular penicillin treatment

ProbioticProbiotics will be given to 30 hospitalized patients with regular penicillin treatment

Study Status


Start Date: October 2012

Completed Date: October 2013

Phase: Phase 3

Type: Interventional


Primary Outcome: period of disease

Secondary Outcome: analysis

Study sponsors, principal investigator, and references

Principal Investigator: Leonid Livshits, MD

Lead Sponsor: Ziv Hospital


More information:

Discuss Penicillin