Throat Pain | The Effectiveness of Probiotics for the Therapy of Acute Pharyngotonsillitis in Adult Patients
Throat Pain research study
What is the primary objective of this study?
The addition of probiotics to the routine therapy of Acute Pharyngotonsillitis in adult
patients may shorten the duration, and reduce the severity of the disease.
Who is eligible to participate?
- Age over 18 years
- Acute pharyngotonsillitis for which hospitalization for intravenous antibiotic
treatment and/or fluids is needed
- Current therapy with systemic prednisone or equivalent at 20 mg/d for more than 10
days prior to inclusion
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:Placebo1 tablet 2 times daily
Drug:Probiotics1 tablet twice daily
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Penicillin Ghospitalization of 30 patients given penicilline intraveniously for 72 hours
Placebo30 hospitalized patients will be given placebo with a regular penicillin treatment
ProbioticProbiotics will be given to 30 hospitalized patients with regular penicillin treatment
Start Date: October 2012
Completed Date: October 2013
Phase: Phase 3
Primary Outcome: period of disease
Secondary Outcome: analysis
Study sponsors, principal investigator, and references
Principal Investigator: Leonid Livshits, MD
Lead Sponsor: Ziv Hospital