Community Acquired Pneumonia | Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Pneumonia and Pneumococcal Vaccine
Community Acquired Pneumonia research study
What is the primary objective of this study?
The aim of this study is to test if BPS (Bacterial Pneumonia Score) guided antibiotic use in children with non severe community acquired pneumonia (CAP) and pneumoccocal vaccine will reduce antibiotic use as compared to standard care practice (current guidelines for CAP).
Who is eligible to participate?
Inclusion Criteria: - Children aged 3-60 months assisted as outpatients for non severe community acquired pneumonia and pneumoccocal vaccine and complete immunisation with pneumoccocal vaccine. Exclusion Criteria: - Wheezing - Severe pneumonia - Pulmonary or cardiovascular chronic disease - Antibiotic use in the previous two weeks - Hospitalization for any reason in the previous two weeks
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Community Acquired Pneumonia
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Behavioral:BPSIn this study a strategy based on BPS guided antibiotic use in children with community acquired pneumonia implementation will be compared with enforced guideline.
Behavioral:GuidelineStrategy based on enforced guideline guided antibiotic use
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
BPS (Bacterial Pneumonia Score)Strategy based on BPS guided antibiotic use
GuidelineStrategy based on enforced guideline guided antibiotic use
Start Date: July 2013
Completed Date: July 2014
Primary Outcome: Use of Antibiotics in Each Group
Secondary Outcome: Treatment Failure in Each Group
Study sponsors, principal investigator, and references
Principal Investigator: Fernando A Torres, MD, PhD
Lead Sponsor: Hospital General de Niños Pedro de Elizalde
Moreno L, Krishnan JA, Duran P, Ferrero F. Development and validation of a clinical prediction rule to distinguish bacterial from viral pneumonia in children. Pediatr Pulmonol. 2006 Apr;41(4):331-7. Erratum in: Pediatr Pulmonol. 2006 May;41(5):494.