Glaucoma | Evaluation of Omeprazole Effect on Glaucoma

Glaucoma research study

What is the primary objective of this study?

Omeprazole is a safe drug listed in OTC drug due to its safety. It acts by irreversible inhibition of K/H ATP ase pump and also Na/K ATP ase, Na/H ATP ase.Considering these actions the effect of omeprazole on decreasing intra ocular pressure is an issue of debate.In this Randomized Clinical Trial conducted in labafinejad hospital, patients with glaucoma who need to take omeprazole due to GI problem are evaluated in two groups including placebo and drug users. The effect will be finally assessed.

Who is eligible to participate?

Inclusion Criteria: - patients with glaucoma - 18 to 70 years - POAG patients, Pseudoexfoliation - no history of other systemic disease - no history of intraocular intervention - no history of H2 blocker or PPI consumption during the past month consuming 2 or less topical anti-glaucoma medication - no present immune deficiency - no addiction habit Exclusion Criteria:

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?


Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.



Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.



Study Status

Unknown status

Start Date:

Completed Date:

Phase: Phase 1

Type: Interventional


Primary Outcome:

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Collaborator: Ophthalmic Research Center

More information:

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