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Dyspepsia | Comparison of Pantoprazole and Ranitidine in Dyspepsia

Dyspepsia research study

What is the primary objective of this study?

The H0 hypothesis of the study is there is no difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department. The H1 hypothesis is there is difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department.

Who is eligible to participate?

Inclusion Criteria: - Epigastric pain - Older than 18 years old Exclusion Criteria: - Diagnosed as cholecystitis, pancreatitis, myocardial infarction, etc.. at the end of the emergency deparment evaluation period. - Pregnancy - Patients with unstable vital signs - Patients used anti-acid, H2 receptor blockers and proton pomp inhibitors in the last one hour. - Allergy to H2 receptor blockers and proton pomp inhibitors. - Patients denied to give inform consent and who are illiterate

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Dyspepsia

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:Pantoprazole33 patients

Drug:Ranitidine33 patients

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

pantoprazoleIntravenous pantoprazole 40 mg flacon

ranitidineIntravenous ranitidine 50 mg

Study Status

Completed

Start Date: October 2012

Completed Date: January 2013

Phase: Phase 4

Type: Interventional

Design:

Primary Outcome: Visual Analogue Scale Score

Secondary Outcome: Need for Additional Drug

Study sponsors, principal investigator, and references

Principal Investigator: Cenker Eken, Proffesor

Lead Sponsor: Akdeniz University

Collaborator:

More information:https://clinicaltrials.gov/show/NCT01737840

Welling LR, Watson WA. The emergency department treatment of dyspepsia with antacids and oral lidocaine. Ann Emerg Med. 1990 Jul;19(7):785-8.

Discuss Ranitidine