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Agitation | Effect of Deksmedetomidine and Remifentanil in Extubation Agitation

Agitation research study

What is the primary objective of this study?

To compare the effect of two different agents deksmedetomidine, remifentanil and placebo, agitation and recovery condition, on nasal septum operation.

Who is eligible to participate?

Inclusion Criteria: - Adult patients Exclusion Criteria: - patients with any sensitivity each drug

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Agitation

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Drug:deksmedetomidinedeksmedetomidine infused during operation 0.2 mcg/kg/hour

Drug:RemifentanilRemifentanil infused during operation 0.2 mcg/kg/min

Drug:SalineDuring operation saline infused equal vol├╝me of deksmedetomidine and remifentanil

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Deksmedetomidine infusionTo prevent agitation deksmedetomidine infused during operation and at the end of surgery agitation scor measured by Riker sedation agitation scale.

Remifentanil infusionTo prevent agitation remifentanil infused during operation at the end of surgery agitation scor measured by Riker sedation agitation scale.

Saline infusionSaline infused during operation and at the end of surgery agitation scor measured by Riker sedation agitation scale.

Study Status

Unknown status

Start Date: April 2014

Completed Date: June 2014

Phase: Phase 4

Type: Interventional

Design:

Primary Outcome: To asses postoperative agitation score by Riker sedation agitation scale

Secondary Outcome: Yo asses postoperative side effects emesis, vomitting or pain

Study sponsors, principal investigator, and references

Principal Investigator: Reyhan Polat, MD

Lead Sponsor: Diskapi Yildirim Beyazit Education and Research Hospital

Collaborator:

More information:https://clinicaltrials.gov/show/NCT02104297

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