Sepsis | Identification Sepsis Related Single Nucleotide Polymorphism (SNP) by Whole Exome Sequencing
Sepsis research study
What is the primary objective of this study?
Sepsis is a common cause of death in intensive care unit, timely and accurate diagnosis and
treatment directly affect the survival rate. Single nucleotide polymorphism (SNP) was
promising genetic biomarker for sepsis patients. The present study was designed to screen
several SNP by whole exome sequencing which evaluate the sepsis related snp site in order to
be a new target for the treatment of sepsis.
Who is eligible to participate?
- Clinical diagnosis of sepsis
- Patients who agree with the study
- Aged <18 years;
- Into the group who died within 24 hours;
- Agranulocytosis (<0.5 × 109 / L);
- Combined HIV infection.
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Start Date: January 2013
Completed Date: December 2015
Type: Observational [Patient Registry]
Primary Outcome: sepsis related SNP site
Study sponsors, principal investigator, and references
Principal Investigator: Huijuan Wang, Dr
Lead Sponsor: Chinese PLA General Hospital