Chronic Sinusitis | Genetic Factors in Chronic Sinusitis

Chronic Sinusitis research study

What is the primary objective of this study?

The purpose of this study is to learn more about the genetics of chronic sinusitis and identify genes involved in chronic sinusitis.

Who is eligible to participate?

Inclusion Criteria: - Age> 18 years - Diagnosis of chronic sinusitis or normal sinuses (with verification by imaging.) You must have a recent CT scan showing either normal sinuses or the presence of sinus disease. Exclusion Criteria: - Genetic or acquired immunodeficiency - Ciliary dyskinesia - Cystic fibrosis - Autoimmune disease - Cancer of the sinuses

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Chronic Sinusitis

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

controlAdults with normal sinuses

caseAdults with chronic sinusitis and positive findings on imaging.

Study Status

Unknown status

Start Date: April 2009

Completed Date: March 2017


Type: Observational


Primary Outcome: Association of genetic variation with CRS disease status

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Jayant Pinto, MD

Lead Sponsor: University of Chicago


More information:

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