Chronic Sinusitis | Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis
Chronic Sinusitis research study
What is the primary objective of this study?
That high-dose steroid applied to the nasal cavity immediately post-operatively will improve
olfaction and healing following endoscopic sinus surgery.
Who is eligible to participate?
- hyposmia and nasal obstruction for >12 weeks
- bilateral nasal polyposis
- candidate for surgery
- non-English speaking
- will not attend follow up appointments
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:pulmicortapplied to nasal packing after surgery
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Single Arm; nostrils as experimental and comparatoreach subject serves as their own control with one nostril being treated with pulmicort and one not
Start Date: September 2010
Phase: Phase 3
Primary Outcome: olfaction
Secondary Outcome: Sinonasal health
Study sponsors, principal investigator, and references
Principal Investigator: Garrett R Griffin, MD
Lead Sponsor: University of Michigan
Collaborator: American Rhinologic Society