Chronic Sinusitis | Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis
Chronic Sinusitis research study
What is the primary objective of this study?
The propose of this study to determine efficacy and complication of gentamicin nasal irrigation in chronic rhinosinusitis
Who is eligible to participate?
Inclusion Criteria: - Chronic rhinosinusitis patients who were followed in pediatrics allergy clinic at Siriraj hospital between January 1, 2005, and February 28, 2011 - Gentamicin nasal irrigation usage for longer than 3 months Exclusion Criteria: - Patients who used azithromycin prophylaxis within 1 year before and 6 months after started gentamicin nasal irrigation - Patients received IVIG within 1 year before and 6 months after started gentamicin nasal irrigation - Patients underwent endoscopic sinus surgery within 1 year before and 6 months after started gentamicin nasal irrigation - Patients received IT within 1 year before and 6 months after started gentamicin nasal irrigation
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Start Date: March 2011
Completed Date: March 2012
Primary Outcome: Frequency of sinusitis
Secondary Outcome: Complications of gentamicin nasal irrigation usage
Study sponsors, principal investigator, and references
Principal Investigator: Nualanong Visitsunthorn, professor
Lead Sponsor: Mahidol University
Fokkens W, Lund V, Mullol J; European Position Paper on Rhinosinusitis and Nasal Polyps group. European position paper on rhinosinusitis and nasal polyps 2007. Rhinol Suppl. 2007;20:1-136. Review.