Non-Melanoma Skin Cancer (NMSC) | Optical Frequency Domain Imaging for Non-melanoma Skin Cancers

Non-Melanoma Skin Cancer (NMSC) research study

What is the primary objective of this study?

The purpose of this research study is to find out if a non-invasive imaging device called Optical Frequency Domain Imaging (OFDI) can help doctors to see the tissue and blood vessels that are related to non-melanoma skin cancers. OFDI was designed to see microscopic details of your skin without needing to use any invasive techniques such as surgery or biopsy.

Who is eligible to participate?

Inclusion Criteria: 1. Male or female subjects with Fitzpatrick skin type I-VI 2. Subjects with ages between 18 and 80 years of age 3. Presence of at least one NMSC lesion Exclusion Criteria: 1. Subjects with active localized or systemic infections 2. Subjects participating in potentially confounding clinical studies of investigational therapies, either drug or device. 3. Subjects taking any topical/systemic chemotherapy or immunosuppressants 4. Subjects who are pregnant and/or breastfeeding 5. Subjects with tape adhesive allergies

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Non-Melanoma Skin Cancer (NMSC)

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Device:OFDIImaging of skin

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

NMSC ImagingOptical Frequency Domain Imaging (OFDI) will be used to look at non melanoma skin cancer (NMSC) lesion(s).

Study Status


Start Date: March 1, 2017

Completed Date: December 2019

Phase: N/A

Type: Interventional


Primary Outcome: Successful imaging of lesion

Secondary Outcome:

Study sponsors, principal investigator, and references

Principal Investigator: Benjamin Vakoc, PhD

Lead Sponsor: Massachusetts General Hospital


More information:

Discuss Skin cancer