Suicide, Attempted | Pilot Trial of Inpatient Cognitive Therapy for the Prevention of Suicide in Military Personnel

Suicide, Attempted research study

What is the primary objective of this study?

The broad objective of this research is to effectively utilize a unique window of opportunity during the hospitalization period following a recent suicide attempt to deliver a brief and targeted intervention for traumatized individuals.

Who is eligible to participate?

Inclusion Criteria 1. Suicide Attempt (Recent or Lifetime) Psychiatric Admission 2. History of Trauma 3. Baseline Completed within 48 Hours of Admission 4. Over the Age of 18 5. Provides Informed Consent Exclusion Criteria 1. Self-Inflicted Harm with No Intent or Desire to Die 2. Medical Incapacity to Participate 3. Current State of Active Psychosis 4. Expected Discharge within 72 Hours of Admission

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Suicide, Attempted

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Behavioral:Post Admission Cognitive Therapy (PACT)Individual psychotherapy; 6 sessions; 60-90 minutes in duration; administered over preferably 3 days of psychiatric hospitalization

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Post Admission Cognitive Therapy (PACT)Six (6) 60-90 Minutes Sessions of Post Admission Cognitive Therapy Delivered Preferably Over 3 Consecutive Days of Inpatient Stay

Enhanced Usual Care (EUC)Treatment As Usual and Study Assessment Services

Study Status


Start Date: July 2008

Completed Date: December 2018

Phase: N/A

Type: Interventional


Primary Outcome: Repeat Suicide Attempts

Secondary Outcome: Depression

Study sponsors, principal investigator, and references

Principal Investigator: Marjan Holloway, Ph.D.

Lead Sponsor: Henry M. Jackson Foundation for the Advancement of Military Medicine

Collaborator: Congressionally Directed Medical Research Programs

More information:

LaCroix JM, Perera KU, Neely LL, Grammer G, Weaver J, Ghahramanlou-Holloway M. Pilot trial of post-admission cognitive therapy: Inpatient program for suicide prevention. Psychol Serv. 2018 Aug;15(3):279-288. doi: 10.1037/ser0000224.

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