Anxiety | Computerized Anxiety Treatment for Suicide

Anxiety research study

What is the primary objective of this study?

The purpose of this study is to test the effectiveness and usability of multiple computer-based treatments for mood and anxiety relevant risk factors. The target of the treatment is related to cognitive stress, which has been shown to be associated with a variety of negative mental health outcomes such as Post-Traumatic Stress Disorder, suicidal ideation, and substance use disorders.

Who is eligible to participate?

Inclusion Criteria: - Meet diagnostic criteria for a primary Axis 1 anxiety disorder or meet diagnostic criteria for a unipolar mood disorder along with an Axis 1 anxiety disorder. - Show evidence of current suicidal ideation (BSS above 6. - Show elevated AS indicated by scoring at or above the community sample mean on the ASI-Cog (above 9. Exclusion Criteria: - No significant medical illness (e.g. sig cardiovascular disease, epilepsy, stroke). - Current or past psychotic-spectrum disorders or uncontrolled bipolar disorder - No current substance dependence - Must be an English speaker. - Must be 18 years or older. - Must have normal or corrected vision - Cannot begin treatment/therapy within 1 month of baseline. - Cannot begin a new medication within 3 months of baseline.

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?



Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Other:Cognitive Anxiety Sensitivity Treatment

Other:Physical Health Education Training

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

InterventionThe anxiety risk reduction condition will be a combination of psychoeducation plus Cognitive Bias Modification (CBM-I) for anxiety sensitivity (AS). The psychoeducational component will focus on the nature of stress and its effect on the body. Interoceptive exposure (IE) exercises, designed to correct the conditioned fear to these bodily sensations, will be explained and practiced.

ControlThe control condition will be a combination of information about general health and wellness (e.g. diet, exercise etc.) plus an inert Cognitive Bias Modification (CBM-I) task.

Study Status


Start Date: October 2013

Completed Date: July 2016

Phase: N/A

Type: Interventional


Primary Outcome: Anxiety Sensitivity Index-3 (ASI-3)

Secondary Outcome: Beck Suicide Scale (BSS)

Study sponsors, principal investigator, and references

Principal Investigator:

Lead Sponsor: Florida State University


More information:

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